what is your experience in combating negative symptoms?

Hi, I’m new to the forum, I can’t write properly because of the difficulties I face with Negative Symptoms. I’ve already tried Panax Ginseng and it improved my negative symptoms by only 20%, but it gave me anxiety and I decided to stop. Afterwards I also tried Fish Oil, but it gave me an improvement of only 10%. The improvement with these supplements wasn’t enough for me, both didn’t make me work again, but it was better than nothing.

I currently spend most of my time in bed, go to the gym twice a week, speak with few words

@everhopeful @Aziz @Bowens @velociraptor @Andrey @Green @Kxev @ZombieMombie and more, Tell me about your experience with supplements, medications and therapy, I would love to know more about how it was



Welcome @Andres_Britas .

If you find yourself in need of help, just tag a moderator. Type the @ symbol, then our names

@ZombieMombie , @ninjastar , @Moonbeam, @rogueone, and @Bowens

Enjoy your stay with us!

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I have found success in reducing my antipsychotic dose under the guidance of my doctor. Looking for an anti-depressant that works for you is another option. However these options don’t work for everyone and in some cases lowering your antipsychotic dose can be a bad thing.

Welcome to the forum, hope you can find some support here, I find it a very helpful place!


Some people think Sarcosine is effective at combatting negatives and cognitive.

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Welcome, personally Abilify has been the most effective for my negative symptoms. Its a partial dopamine agonist so it doesn’t fully block dopamine like other meds. There is also Rexulti and Vraylar. Some users claim that Sarcosine help them but it didn’t for me. I find that caffeine pills 3x 200mg daily help a bit and lift my mood.


I’m also on abilify 15 mg, so far it’s still not working for negative symptoms in 20 days of use.

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Maybe give it more time. Also Ritalin, Adderal, Wellbutrin or Modafinil can improve negative symptoms. Wellbutrin didn’t work for me though. Dr refused to prescribe Ritalin or Adderal as they may worsen positive symptoms but here on the forum some users are on them no problem.

Sarcosine gives me a mild but noticeable cognitive boost. I’m not sure if it helps with negs or not at this point. Could have been placebo effect there. Amyloban 3399 has been the real surprise as supplements go. @Andres_Britas - I suggest you read the Sarcosine and Amyloban discussions first and then shoot any specific questions you have my way.

Fish oil really only improved the speed at which stuff shot through my digestive system. Too much of it can be … messy.




Welcome, @Andres_Britas
Happy New Year !

My experience with negative symptoms was a nasty one. For 3 and a half years I was bedridden. During that time I uselessly tries sarcosine, nac and pregnenolone, with only placebo-level improvements. After that I messed with my meds for the first time WHICH I DON’T RECOMMEND. I felt better for a short while, but then I started getting paranoid and hearing voices again. Upon resuming medication, my negatives got better but I put it down to luck. Since then I’ve relapsed one more time, again after quitting meds on my own. Fortunately the negatives didn’t come back in full force, on the contrary. I am now in a much better place and I am able to hold down a job that isn’t too stressful.

Tldr: couldn’t find an efficient supplement for negatives. After two relapses, they got better by themselves but it’s a very risky gamble and I discourage you to follow my example.


I manage my negatives with coffee and Wellbutrin (an ad). I still sleep 11-12 hours though.

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Can try probiotics. Apparently helps with serotonin though couldn’t notice any change as I take multiple food supplements.


It will take 4 to 6 weeks for all effects to show up properly.

There are antidepressants which can help with negative symptoms.

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I have the oposite problem

To much energy


COQ-10 apparently helps with energy release as well. But it’s expensive, $1/a pop.

Easiest way and most effective way, antidepressants.

Abilify helped me go to occupational rehab as well.

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caffeine and exercise.


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Is it hypo/manic episode?

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Usually its borderline

I have up coffee and it helped a bit.