Antipsychotics that are better than others with negative symptoms?

Medications
1

Hey guys,

I realize I may be embarking on an impossible journey, but I am wondering if there are any antipsychotics out there that are better than others at not aggravating negative symptoms, or good at treating them as much as possible. I switched from 5mg Abilify last year to 10mg and I am certain it is this that is causing me hell as now I am unable to focus when someone says something to me, unable to focus on reading books, zero motivation, lost my interests and have gradually become more and more emotionally numb to the point that I feel no emotion now other than a huge depression in which I find nothing interesting or beautiful. I also have almost no thoughts anymore. I’m alive but not really. I have an appointment with my psychiatrist in a couple days and I am wondering if you all have had experience with antipsychotics that help negative symptoms as much as possible. I’d like to switch meds. I know it’s the Abilify because while I had some of these symptoms a little bit before, the ones I did have, have become incredibly worse since the dose was upped. Thank you very much in advance for any help.

2

Yes it’s the aripiarzole.
When I was on 10 mg I was a dead person walking. I’m now on 5mg and feeling somewhat better.

Sorry I can’t give recommendations on other aps. If I had to I would go with geodon because it has weak anticholinergic properties. Anticholinergic side effects include memory issues, eye issues and food movement issues. In some people

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3

Sometimes the situation the schizophrenic is in is not due to the anti-psychotic medication but the person themself.

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4

I swear by vraylar. I love it. I recently got on Strattera for focus. I have add. I have delusions and negative symptoms only. I’m fat from meds and diet. I don’t work or attend school. I got schizophrenia 9 years ago.

I’m surprised more people aren’t on vraylar or have not heard of it. It can be pricey. I’m actually looking into a newer med called lumateperone.

Good luck.

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5

My psychiatrist told me that Abilify is the best they have for negative symptoms and its true.
I was social, able to work and hang out with my friends while on Abilify 25mg.
Now I am on Latuda 80mg and never go out of my bed, my parents get my meds and food.

I switched to Latuda because I developed addiction issues from Abilify. My psychiatrist said its a side effect of Abilify that occurs in some ppl. I had issues with gambling, hypersexuality/promiscuity, compulsive shopping, weed addiction and binge eating. The weed addiction brought more psychosis.

All these stopped when I switched to Latuda but I stopped being social and now suffers from negative symptoms. For me I would rather have negative symptoms than not being able to pay my debts which my parents luckily paid. I was drawing cash from my visa. Now I closed my visa and bank account.

6

There is many Abilify lawsuits, more than 2600!:

For example, compulsive gamblers filed lawsuits seeking reimbursement for their losses. Compulsive eaters want money for medical costs, including weight-loss surgery. People who engaged in hypersexual activity want compensation for their financial and emotional costs from a divorce, for example.

Abilify lawsuits claim the drug’s manufacturers failed to warn doctors and consumers that their antipsychotic medication could cause compulsive gambling, eating, sex and shopping. As ofJune 2019, more than 2,600 Abilify lawsuits had been filed in federal court against Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co.

7

I have exactly the same situation. I’m not sure if this is related to pills. I am taking risperidone 2 mg

8

Fanapt is fairly free of side effects.

9

Some meds made me dead feeling and others helped with it. I found amisulpride and risperidone helped the best.

10

DMG supplement is good for negative symptoms, I mean it help to feel emotions in a healthy way.

11

Hi longamor, i find clozaril to be the best ap to treat the negative symptoms, i have been on so many ap over the past 25 years i was 20 when i first got ill and i am 45 now the side effects of clozaril can be tough and its not for everyone, hope you find an ap that works for you!

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12

Why don’t drs use it then to treat negative and cognitive symptoms?

13

Clozapine is used as a last resort because it can have life-threatening side effects like low white blood cells count.

There is nothing for negative and cognitive symptoms right now but KarXT (Xanomeline+Tropsium) showed much better 2.7x efficacy than current meds in treating all SZ symptoms ( 9pts Current meds vs 24 pts KarXT SZ scale improvement).

It will be in Clinical Trial 3 end of this year so it should be available in 5 years.

14

Its a health supplement, drug companies can’t make profit out of it thus doctors not usually prescribe health supplements to patients.

For negative symptoms dmg is best and for cognition omega 3 is best.

15

Nac sarcosine all supplements and hardly any doctor prescribe it though several reported benefits from it.

16

Can’t they make a similar more powerful med and market it?

17

Drug companies can’t do it. But supplement companies can formulate such a thing if every ingredient belongs to supplement group.

18

In Canada meds are free or a few dollars.
How do they make profit from it?

19

Its funded by govt I think so even though users not pay much for it govt or health insurance companies paying to such drug companies on behalf.

20

I don’t know. I have tried tons of supplements wasting thousands of dollars without any improvements. I even tried Lithium Orotate.
I already tried DMG. Only thing left for me to try is Sarcosine. I ordered 250g from China on eBay.

I will soon try Risperdone+Sarcosine and will let you guys know if my severe negative and cognitive symptoms improve.