Non-antipsychotic Drugs May Improve Cognition of Schizophrenia Patients

News
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Some interesting drugs that may help in improving cognition in Schizophrenia:

Conclusion:

Available data do not support the superiority of non-antipsychotic drugs vs. placebo for cognitive enhancement in schizophrenia.

However, Preliminary results indicate

  • mirtazapine,
  • mianserine,
  • lamotrigine,
  • tandospirone,
  • cyproheptadine,
  • valacyclovir
  • omega-3 fatty acids

as the most promising compounds, however no definitive conclusions can be drawn in the light of small sample size studies.

Study Details:

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Interesting. I have been taking Omega 3 fatty acids for years and I developed mild cognitive impairment while taking it. I still take it. I was on cyproheptadine for years, for the treatment of nightmares, and when I developed memory issues, my pdoc discontinued it, thinking that it was affecting my memory. Afterward, my memory did improve substantially, but, I still have noticeable memory problems.

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Just to follow up on this - here is a link to one of the substances, for more information:

Interestingly:

“According to a small study, cyproheptadine hydrochloride has been found to improve sleep, calmness, as well as mood and energy levels, and to improve both negative and (sometimes even) positive psychotic symptoms in a subgroup of chronic schizophrenics who do not respond (either completely or sufficiently) to other therapies”

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I dont have schizophrenia per say, but I do have bipolar type 1 and I am pretty sure that the lamictal and Omega 3 EPA fish oil are helping me - very interesting post @SzAdmin - thank you for posting this