and may explain why my blood sugar shot down to 44 the other night. No one warned me of potential interactions between glipizide, metformin and Paxlovid…but check out this chart:
The only med I was told I was taking that was a problem with taking Paxlovid was Atorvastatin, and I discontinued that…
According to the chart, there is “moderate interaction that requires caution and close monitoring.” Thank God I was on my toes and caught it.
Frankly, if I wouldve went into a coma from low blood sugar…which I’ve read can happen below 40, my parents my have been able to file quite a lawsuit. This is really something that I should have been told.
Yeah that is scary. Glad you picked it up and no wonder you were feeling weird. Really does pay to be proactive with all your healthcare. We tend to think endlessly about the psych meds but other things are just as important.
I am glad you spotted it @Bowens
That’s nothing less than negligence that the other drugs you were taking were not reviewed when you were put on that.
Is healthcare where you are seeming a bit rushed due to covid pressures still?
Here in the UK they do not have enough doctors and nurses, and the waiting list for surgery is very high.
Looks like from what I have seen they’re going at speed to reach demand
I know I give the doctors a hard time, but they do work very hard. But, that’s not an excuse to nearly put you into a coma!
looks to me like the ethiopian flag.
I contacted an online doc because it was the weekend and Paxlovid has to be taken 5 days from symptoms. The funny thing is she DID review med interactions and mentioned nothing about those two. I also talked to my GP 2 days later, 2 days into paxlovid regemine, and she didnt say anything about potential interactions either. So I dunno wtf…
Thanks @Bowens I had the Paxlovid too for Covid maybe a month ago. I have been having some issues similar to yours.
That’s scary! Are you going to show the chart to your dr?
my next appointment with them is is by video call so it would probably be too small for them to see. I will bring it up though
If it is a side effect it must be rarer. I’m on some meds mentioned. The only ones the hospital adjusted was my statin and my geodon. They said all my blood sugar meds were fine. My blood sugar never dropped that low. I think it increases the strength of the meds. So you might have been getting a slightly stronger dose, when mixed with the paxlovid.
YEah, I dont really think its the docs fault…I found this document that says there is no expected interaction between it and glipizide. It may be that the data on interactions is not uniformly known because drug is so new? IDK , but if it wasnt the Januvia, which I’m beginning to doubt that it was, it was almost certainly an interaction between glipizide and paxlovid. I’ve been taking diabetic meds for years now and have never had blood sugar that low. Something changed.
https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2646
@Bowens Do you work? If you don’t and can’t work because of your sz/sza or other MI, your parents may not be able to file a lawsuit in the event of your wrongful death, at the hands of others, in some states. Especially if you don’t have a family that is financially dependent upon you.
Unfortunately in a lot of states, we are only worth the amount of money we pull in.
Holy cow!
40 blood sugar number can be deadly!
I get nervous when my number falls down into the 80s!
Yeah, it was scary. I started shaking and sweating and felt awful. I couldnt think clearly. Then I took reading and it was 44. I quickly drank some soda and ate a brownie since we had no orange juice on hand.
The good thing it only happened once. So doctors consider it a fluke. If it happens frequently, definitely need to be concerned. The paxlovid is only a five day course, so not long. I had some awful symptoms while on it. It was very unpleasant. It wasn’t like the iv antibodies at all.
I highly recommend getting a continuous glucose monitor. Then you can set it to alarm you, when it’s too high or getting too low. I have the dexcom 6. It’s very nice and not uncomfortable to wear at all. I change the sensor every ten days and the transmitter every three months. It’s an app you put on your phone, so it continuously reads it. Unlike the libre, you don’t have to put your phone to it to get a reading each time. It’s just always reading it.
I’m glad you are ok @Bowens!
Man what a close call!
While I was on that course I noticed it dropping lower at night…80’s and 70s but I monitored closely and always ate something to raise it. So I expect that interaction was causing these lower blood sugars as well. But they werent as severe as that one time. I believe that it was indeed the paxlovid increasing glipizide potency. Either way, I’m off it now. But this is definitely something that I need to report and have noted.
This is a good idea.
Okay. Yah, thankfully you are off paxlovid now. Definitely report it to the drug company, so they know.
I would advocate for one. Your doctor will probably be very much okay with it. The only issue would be which are covered by your insurance.
