I think antagonist and agonist don’t make much of a difference since they both blocks dopamine
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That could be possible but I relapsed twice and my functioning is still similar, usually schizo positive symptoms gets better as we age
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Partial dopamine agonists can be dopamine agonists/boosters and dopamine antagonists/blockers at the same time.
“Partial agonists have a lower intrinsic activity at receptors than full agonists, allowing them to act either as a functional agonist or a functional antagonist”
I felt that I lost my energy and emotions on meds that aren’t partial dopamine agonists.
Yea agonist increases dopamine in the mesolimbic track I think while reducing D2 dopamine but anyway ziprasidone is the most prescribed antipsychotic in America so I see no harm in trying it out
It’s the high dose that caused the problem I was on 4mg risperidone so I know
I had that problem even on 80mg Latuda, 3mg Risperdal, 10mg Zyprexa, etc I didnt have it even on 25mg Abilify.
Schizo itself can also cause that problem when I am having psychosis I felt loss of emotion ,advolition as well, 20mg abilify makes my feeling a bit out of whack
I couldn’t cry on antipsychotics at all
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Yea true I had more energy and emotions before sz but still I have them post sz the most on Abilify especially low Abilify doses.
I couldnt cry on antipsychotics too but I think I did cry back when I was on 10mg or lower Abilify?
At 4mg risperidone I was just sleeping whole day according to my parents. I wanted to try ziprasidone but the hospital doesn’t sell it anymore even though it had been approved by my country 's fda
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I was like that but with caffeine, nicotine and time it improved a bit. I can play video games everyday for like 2-3hrs.
I also walk in the house with a step counter sometimes.
Now I never sleep during the day and sleep 9h per night. What meds are you on? I like our discussion 
Please go see a psychiatrist and ask for a switch to a lower dose to see how your body react first before switching to ziprasidone. I think at 10mg abilify I still have some occasional symptoms but I can live with them so I am ok with it
So I think if your symptoms isn’t too heavy, it is ok to stay on a lower dose and have some occasional symptoms then to stay on a high dose and be on the bed the entire day
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@swordiebrom A reminder we don’t prescribe here and there’s a difference to suggesting and prescribing.
We are all different and react to meds differently. Telling a person to take a med or another simply over the internet isn’t good advice and it’s certainly something we avoid. Please consider this a warning. It’s ok to suggest things that may work but we aren’t doctors nor look to replace that in members lives.
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Yes, in all my suggestions I recommended him to see a doctor for advice. I don’t think I am in anyway prescribing sorry if my messages are unclear
Just be careful. You don’t know how meds react to the individual and it’s not something we tolerate. Be kind to other members and remember we are all different.
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It is not a rebound
It is because you stop talking any treatment for schizophrenia- a permanent lifelong deteriorating psychosis
How do you know i have schizophrenia, if my doctors think i havent?
I just dont believe in the idea that psychosis should always be treated by medication. Indefinetely. Or that it is always a lifelong and deteriorating disorder. I know of several people who have successfully stopped medication, especially after just one episode. Which doesn’t mean all people can do this or there is no risk.
There is the issue of a return of symptoms. But there is also the issue of rebound psychosis. Both are possible. Hence the great importance of slow and cautious tapering instead of cold turkey quitting. I think that is crucial to understand before a quitting attempt. Even doctors here now acknowledge this and i think this is very important for people’s safety.
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