I was given Abilify 5mg to help reduce prolactin levels.
When they tested me 1 month after starting treatment, they’d actually gone up 10%!
Now it has been about 6 months.
If it’s still high, I will be coming off it. One less tablet for me! (Yay!)
However, if it is a lot lower, it’s a win still and I keep taking it.
It has been determined that the risk of the high prolactin is worth the benefit for the treatment of my symptoms. I was not included in that decision process…
Sorry to bother you all, but I swear one of you posted an article that showed Aripiprazole lowered prolactin in Risperidone patients, but not Amisulpride.
To summarize, we could document the lack of an expected decrease of serum prolactin levels by aripiprazole in the combination with amisulpride. A possible explanation may be found in the fact that amisulpride as a hydrophilic ‘ atypical ’ antipsychotic preferentially blocks tubero-infundibular dopamine D2 receptors that are outside the blood–brain barrier. Therefore, higher doses of antipsychotic agent are needed to reach antipsychotic effects. Consequently, although aripiprazole has a higher affinity for dopa- mine D2 receptors it is not able to occupy enough tubero-infundibular dopamine D2 receptors to lower amisulpride-induced hyperprolactinaemia.
Adjunctive aripiprazole treatment reversed effectively hyperprolactinemia induced by risperidone, but was less effective for that induced by benzamide antipsychotics. [1]
Just to clarify, benzamide antipsychotic means = amisulpride or sulpride