From what I’ve read Ulotaront seems like the better med. for me at least. Marketing?
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Isn’t karXT closer to release than ulotaront?
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I’m not sure. Google says Karxt should be available in the 3rd quarter of 2025 and Ulotaront just finished up its long term safety study in November 2022 so I would think that would make them neck and neck.
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I am under the impression that ulotaront is a stand alone drug, whereas karxt is a combination of two. (one to ameliorate the negative affects of the other), which is why I would also prefer ulotaront.
It won’t be available in the uk until about 2030 by the time it gets NICE approval, so ages anyway.
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KarxT is for negative symptoms?
There’s evidence that it improves cognition, and in terms of other antipsychotics it would be near the top of the heap for negs.
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KarXT company Karuna says application mid 2023, approval April 2024 possible.
Sunovion has many long trials running and says hoping for approval of ulotaront April 2024-March 31 2025 fiscal year. They are not predicting application timeframe for ulotaront. Ulotaront also reported to affect REM sleep cycle.
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