Which antipsychotic or antidpepressant will work for my negative symptoms?

I have had sz for about 13 months. I have a very unique profile: antipsychotics–I have tried risperdal, geodon, zyprexa, saphris.–i am currently on 600mg seroquel + 2mg rexulti. Antidepressants—i have tried trazodone, prozac----i am currently on 10mg brintellix.

Disease profile:
Positive symptoms–intrusive thoughts and paranoia
Negative symptoms (my primary issue)-- very mild avolition, very strong alogia, intermediate difficulty in abstract thinking, very strong lack of spontaneous speech, intermediate stereotyped thinking, mild unawareness of environment
Cognitive symptoms–strong verbal fluency deficit, strong executive functioning deficit, strong inability to think ahead organize and plan

This is a short summary of the symptoms I suffer from. The positive symptoms are mostly under control with medication. However I struggle with extremely persistent negative symptoms the worst of which being alogia. The inability to have conversations greatly lowers my ability to relate to people and have any quality of life. I feel completely isolated. I guess im somewhat lucky to have had only mild negative symptoms with the exeption of my alogia. It’s the only symptom which has persisted throughout my illness. Taking into consideration my disease profile please wrack your brain and come up with any treatment based on what you have heard or read during the duration of your sz diagnosis which can help me overcome this all consuming alogia.

Most antipsychotics don’t work on negative symptoms, but it did seem that Abilify did help me in that regard. I think that is classified as an antipsychotic. The only antidepressant that had any effect on me was Wellbutrin. The med’s can affect people differently. Maybe you can find something that helps with your problems.

we can’t really help you about which med. Everyone is different and the meds work differently for each of us. Talk with your doctor and he will find one that helps the best possible.

Ability is supposed to be one of the most activating antipsychotic. I’m on vraylar which is new and also activating. Good luck

Vraylar (cariprazine) is an excellent AP for Negative Symptoms.

It can be very activating - it was too stimulating for me to handle.

But everyone will react to it differently.

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i am like you and no med has made me talk more

its definitely one of the only antpsychotics that didnt make me sleepy

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