Theories about schizophrenia

at the present there are some theories about the cause of schizophrenia that affirm (also indirectly) that stress in the early adulthood (before the onset of the illness) is not a cause/trigger factor?

there are other theories that could be valid that affirm that positive symptoms of schizophrenia appear with the normal maturational process of the brain or other natural neurobiology process (i.e. synaptic pruning for example) of the brain and so that the onset could be not related to psychosocial stress and stressful life events?

thank you to all

I haven’t read much about the causes or theories about the causes because they admittedly don’t know yet. But it’s interesting for sure.

Do get too excited. I found it to be a reaction to food rust. In ones mother and fathers invierment.

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We already know 99% of causes. 80% genetics, most of the other 20% is from drugs like weed, cocaine etc. Stress and trauma plays a lesser degree. Just lookup wikipedia and studies referenced. The remaining 1% is believed to be from infections and malnutrition during pregnancy.

From wikipedia SZ is a genetic neurodevelopmental disorder:

Genetic disorders, such as [fragile-X syndrome] [Down syndrome] [attention deficit hyperactivity disorder] [schizophrenia][schizotypal disorder] [hypogonadotropic hypogonadal syndromes]

Estimates of the [heritability] of schizophrenia are around 80%, which implies that 80% of the individual differences in risk to schizophrenia is associated with genetics.

Theories about treatment are dopamine, glutamine, serotonin and the new interesting muscarinic receptors theory. Xanomeline stimulates muscarinic M1/M4 receptors which was proven to improme positive, negative and cognitive symptoms. It will be in Phase 3 the end of this year.