Hello, firstly I want to warn about my english it isn’t perfect, but what I want to talk about Is the curing effects of drug named solian. I started taking it about year ago exactly 400 mg of it and 200 mg of clozapine within this time I suffered many negative symptoms, I was afraid to go out side, I lacked motivation of doing anything from simple home responsibilities to things like looking for job, I couldn’t find common language with other people I felt this inside emptiness of emotions, and I had more negative symptoms, like attacks of afraid when trying to do some responsibilities. But then my faith suddenly changed, when I started to take less dose of Solian, exactly 200 mg, I started to feel this inside motivation to do things, and responsibilities, I stoped to feel afraid of it, and also I started to find myself comfortable in contacts with another people. This inside emptiness dissapeared. I even occasional started to feel to motivated, but it wasn’t anyway big problem. Also my memory started to work very fine while when before I always have been forgetting many things and had memory problems. Also I improved my rational mind, what I want to say, is that I started to be britght like more intelligent, it felt like I finally started to use my brain. But after two weeks I again started to feel bad, this all negative symptoms which I described before returned, I was confused I was searching for the cause of this situation. But then after some times the situation repeated. I started to feel good and healthy again. With time I realized that those healing effects of solian last for about week and something about next week I feel again bad. And also that its connected with my sex desire, exactly my sex desire starts to get strong at the week when I feel ill, and i’m becoming to have exactly zero of sex desire when I feel again healthy. After about five months of such a situation, My doctor suggested to start using a mood stabilizer to gain a constant sex desire and since 5 months i’m taking 250mg morning and 250 mg night of convival chrono, I think valproinian acid. When I take it all the time I have the sex desire but my inteligence and memory are weak, and I lack of motivation and I’m not very talkative. When I don’t take the stabilizer about twice in week I again have this alternating mood, like I’m talkative one week and more like logical thinking but my memory still Is very weak without sex desire, but the next week i’m in worse mood i’m not to bright and I have sex desire, and for now I’m continuing with this state. What I want to gain with this post is to get any advice, and I know that probably it would be difficult to find someone with pretty similar situation. But I had to try, maybe someone feel to have experience enough to try to help me.
Solian(amisulpride) is known to cause sexual dysfunction. For that you could add abilify which will decrease prolactin. Its 2nd most effective antipsychotic after clozapine in removing delusions. Plus Solian will not help you with cognition in terms of what you just said like memory. Solian is mostly given for positive and negative symptoms and not for cognitive symptoms.
For cognition you can try other antipsychotics like risperidone(will cause sexual dysfunction), abilify, olanzapine, clozapine etc
You can talk to your pdoc about finding which dose works best for u on Solian.
I don’t know If I understand, you suggest staying with solian 200 mg (morning) with clozapine 200 mg(night) and adding abilify which will decrease prolactin and help with libido? And if abilify helps with sexuality should I also put away convival (mood stabilizer)? i’ve never heard that abilify decrease prolactin when taking solian. But also, my sexuality isn’t fully disabled it’s just temporary disabled for about week when I feel better and it’s back like normal for about next week when my ill symptoms comes back. Also when taking stabilizer the libido is rather constant but cognition and memory goes back down and probably part of negatives comes back. Becouse i’m ill for about 5 years so I’ve been taking other drugs also olanzapine with abilify and as I wrote, before solian(year ago) none drug worked with my negatives and cognitiion. I also have been taking olanzapine with abilify and then my libido I remember was totally disabled. I’m pretty sure that the better memory and logical thinking are results of taking solian, maybe it depends on case of patient, in my case solian worked( but of course partialy). I appreciate your advice, maybe soon I will try it. I want also to ask about another medicine becouse i’ve heard that also good alternative for solian is (cariprazine) vraylar, quite new drug.
Love my solian has helped so much im on 600mg a day with 100mg as prn even losing weight on it which has been nearly impossible on every other ap i have tried
@Markedwithblue2 Just a side note, if you can be brief in your communications, more people will respond. Most people look at that wall of text and go away
I take 800mg of this drug and I am doing well on it.
From what I can gather this drug may be working well for you, but as you say partially. Perhaps you need to take a little bit more?
I used to be obsessed with lowering drugs and tapering off them, but really if something is showing potential to work for you, the dose is irrelevant if you can tolerate it and it actually helps you.
Sexual problems and prolactin aside, this is a good drug from my experience. I have been on 6 AP’s and this one works without a high propensity for diabetes, I have no movement problems like I did on Haldol, and I am not getting obese and being a complete zombie as I was with Olanzapine.
If you have to take these meds, you need to decide what your priorities are, and what side effects are palatable.