I have been taking Seroquel for about 4 years. Currently 700mg (up from 600mg.)
I can speak on it. It takes away about 95% of my positive symptoms. I am able to stay in College and focus when I need to. It’s been the best and only AP that has worked for me. I have tried Risperdol, Latuda, and Abilify, and none of them worked.
The weight gain was in the first year or two. I have since stopped gaining weight (thank god,) but have a hard time losing it. But the main thing is that I have “peaked” so to speak with weight gain and it no longer is causing me to gain weight.
I do have issues with the amount of sleep it causes me. This was the reason I tried the other AP’s, but again they didn’t cover my symptoms so I always came back to Seroquel. I sleep about 10-12 hours a night, which is pretty annoying. But I find that if I don’t eat late, and I go to bed before 12pm I typically only sleep 10 hours. (This is my biggest problem with the med, but not enough to make me try switching anymore.)
It’s a great med and all things considered I’m happy with it.