Thats an average of over 13 grams of sarcosine a day - thats much, much higher than any research supports and I think the researchers would say that you risk brain damage that that high level. (overstimulation of brain cells by taking too much, is a danger researchers have said to me)
Don’t do that again please - really bad for your brain.
Some of what I believe is the related research:
NMDA Receptor & Glutamate Excitotoxicity
Glutamate is a predominant excitatory neurotransmitter in the mammalian CNS. When intensely activated, it can be toxic to neurons in a range of acute CNS injury conditions,[5] including stroke,[6] hypoglycemia,[7] trauma[8] and status epilepticus.[9] Excess glutamate is also implicated in neurodegenerative conditions[10] with involvement of the NMDA subtype
From:
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and:
“Glutamate receptors are implicated in a number of neurological conditions. Their central role in excitotoxicity and prevalence in the central nervous system has been linked or speculated to be linked to many neurodegenerative diseases, and several other conditions have been further linked to glutamate receptor gene mutations or receptor autoantigen/antibody activity.”
source:
More related reading about excitoxicity and how it results in death of brain cells:
and
Excitotoxicity, which was first described by Olney in the nineteen-seventies1, involves the activation of glutamate receptors in the central nervous system (CNS). Glutamate, an excitatory amino acid, activates different types of ion channel-forming receptors (ionotropic) and G-protein-coupled receptors (metabotropic) to develop their essential role in the brain. However, high concentrations of glutamate, or neurotoxins acting at the same receptors, cause cell death through the excessive activation of these receptors.
@anon93437440 Ditto. It’s pretty likely you’re setting yourself up for a very nasty bipolar-manic type power dive and crash into severe depression. Don’t want to see you get hurt, and especially not that way. (Been there, done that. Really ugly.)
Some additional details. I would Never go over the 1 to 4 gram per day level of sarcosine that the researchers have tested on so far. Also - don’t use D-serine, Glycine and Sarcosine at the same time - because that could also result in excessively high levels and Excitotoxicity (brain cell death).
Excitotoxicity and cell damage
Excitotoxicity is the pathological process by which neurons are damaged and killed by the overactivations of receptors for the excitatory neurotransmitter glutamate, such as the NMDA receptor and AMPA receptor.
i feel for the original poster, i believe he is trying his best to feel better but maybe a bit too hard, i did a trimester (3 months) studying drug use and misuse and it sounds like you might be abusing the dose a bit (taking too much) but unintentionally, its not your fault, i can see how that can happen, not saying you are a drug abuser but maybe just a bit too keen,
sarcosine is a stimulant and too much of that will make you high and that can be bad,