i was facing difficulties to sleep 3 weeks ago and went to a new doctor
he prescribed to me olanzepine 5 mg & quetiapine 200 and other adjuvent meds
sleep enhanced distinctly and without doubt after these new drugs
recently from a week or so i begin to face some difficulties to sleep
some days i can sleep and other days i cant sleep
so i went to my doctor
he raised the olanzepine to 10 mg and quetiapine still 200 mg
idk
do you think these new meds will help and i will manage to sleep everyday ?
any has an idea about that topic ?
thank you
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Seroquel has a 100% success rate for sleep for me. I usually take 200mg as well.
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That honestly sounds like a wise approach just you will put on a lot of weight with that combination. They are basically 2 of the most heavy sedations meds if your not sleeping on that then you’ll probably find yourself struggling on other meds. 5-10mg would be a big move without the quetiapine. Hard to know exactly what the total dosage conversion and more over effect world be. I would just trust your doctor, it seems like they know what they are doing. You might want to look into life strategies to reduce metabolic stress possibly even something like metformin if that’s not already adjunctive.
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i will be waiting for a week on these new meds untill it reach good conc in my body and see if my sleep enhanced
… in my opinion this recent modification may not change a lot idk really
i hope my problem will be solved who know
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I don’t know what you were taking before, but I would not be happy with that combination. If sleep is the issue 10mg olanzapine should be enough usually on it’s own. Seroquel was more helpful for my sleep at 50mg than it was at 100mg. But I would try the olanzapine alone first.
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Quetiapine is sometimes prescribed off-label as a sleep medication. I think it’s very cruel to put someone on APs and risk the side effects if they don’t specifically require an AP, but I guess that’s another discussion. I actually take it, too. I’m on 200mg, down from 300mg. It helps with sleep, for sure. I do not take it alone, though. I also have Trazadone (100mg), Amitriptyline (50mg), and sometimes Diazepam (10mg)- plenty to make me tired.
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Um, uh…
Aren’t you supposed to know the side-effect profiles of major medications given your profession?
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Do you drink caffeinated drinks?
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The dosage conversion from quetiapine to Olanzapine is apparently 12.5 assuming you were in the ball park of 17.5 Olanzapine total then that’s a 28% increase. Since sequential binding with 2 medications is unknown, I don’t know if it would make the seroquel more potent at the histamine receptior which would increase sedation? We need a doctor.
Also if you think about onset of action then you should be getting mainly a rapid onset.
Clincal observations are still congruent with therapeutic effect so you really couldn’t change things on a scale quicker then 2 weeks-month for proper evaluation of it is working. The body is really going to work on a time scale of months to see real change. Everyone wants rapid answers and instant results but understandly that’s because of how distressing psychosis is and how abrasive the medical system feels during periods of reduced insight. That said the power imbalance in the patient doctor relationship is real. Still someone has to keep us sane, thank god it’s still the meds talking to me in my head 
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If you are a pharmacist, why would you need to ask internet strangers about this? If you aren’t, stop claiming to be one.
To be fair a lot of general practitioners don’t know about antipsychotic medication which is why pdocs exist. Following on from that I have met several doctors from different specialities that do screen questions about medications and can’t place what the medications I take are for. I think the same would be true for pharmacist. There is a difference between pharmaceutical science and general pharmacy. Equally their saynow’s english is heavily broken so maybe they ment they work in a pharmacy as an assistant. That’s also an assumption not necessarily correct on my behalf. Still I completely respect you right to call people out in the safe guarding of community interests. I think it is wrong to assume but it also kind of unhelpful to make an vetted claim. Sorry if that is in anyway an antagonistic view, I think the community deserves people calling each other out when they crazy.
You are correct in the knowledge that if you had general pharmacy training that you would be able to look this stuff up. Also if you were a pharmacist you would never random strangers on the internet with opinions about medication, you would trust your doctor @saynow it doesn’t add up?
I’ve watched this member ask many questions about meds that they should be able to access information on. A pharmacist wouldn’t ask laypeople. Doesn’t make sense.
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Thank you for the clarity, personally for me I think I need to start using the ignore list more often.
you should trust your pdoc and see the results for yourself.
while i was on amisulpride 400mg/day i was having good deep sleep but it worsened my negative symptoms and i woke up lazy, have somnolence and need to sleep again . and there is another drug which is trazodone it have good impact on sleep but it caused me cognition decline also the last choice when all drugs have failed is trying Benzodiazepine. of course you have to discuss these things with your pdoc first before taking it.
I think the zyprexa will help with sleep. I take 22.5 mg of zyprexa at night. It helps me fall asleep.
What’s the problem say. I was awake 42 hours yesterday and I blame the Geodon I went off 10 months ago. The wise tells that it take 1 month per year to overcome the with drawal from your prev meds. So 20 years means that I still have 1 year left ovet with sleep issues. Raising your meds won’t help you sleep. I’m on 900 mgs Seroquel and that doesn’t sedate me at all but take care of my psychosis together with Clopixol depot. But I’m so pleased with that I slept for 15 hours last night.
yeah
really sorry for that
@anon4362788 @ozymandias
yeah i know
in side effects
there is a probability to happen
but who take this meds in real life know better than books and sources
and i d like to know from them
thats the main idea
hi dear
what are you talking about ? 
i m crazy nowdays so i cant understand what are you talking about 
this card
scz members your dear friends
i know you may be in doubt becoz
why i ask if i m pharmacist
if i m scz how could i achieved that ??!!!
but i become scz while i was in college and suffered alot untill i managed to graduate
i stayed 9 years in the university
and i m asking you about meds
to take idea from fellow patients who took these meds in real life to know how meds in real life ?!!!
books or studies which tell us info and there may be a bias in these in information and there are very rare side effects … books and studies talk about these things although these are very rare
and even books talk about very common side effects which even dont happen in real life even !!!
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