Green light to switch medication

From olanzapine to quetiapine.

I’ll just wait until the dust has settled. Am in the middle of moving into new apartment. When that is out of the way I will do it.

Last time I tried did not go well. I stopped olanzapine completely the first day and went on quetiapine. This time I will take quetiapine at night and take 1.25mg olanzapine when I wake up. I am on 5mg olanzapine now. I think it might be wise to have a little of it in my system so the transition is easier. I will probably do this for at least a month, then take 0.625 for another month, then stop olanzapine.

If things go according to plan that is, which they rarely do with stuff like this. But then I will just have to make up things as I go along.

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I wish you good luck. Is that Seroquel?

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Thanks. Yes, correct. 1515

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I used to be on it along with my AP.

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@Mr_Hope, seroquel is not potent as olanzapine…
Are you sure about change…
It’s ok if you don’t have hard symptoms

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I remember coming off zyprexa as tough. But after the first turmoil, things will get better. Wise to wait for calmer waters. Hope you will have no problems at all, obviously. But if you have them, I know you can get through. It seems like you have a good plan. Good luck.

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Yes. My main reason for switching is serious sleep problems on olanzapine. Even on 10mg it’s poor. Lately I have managed with 5mg and a ton of supplements, but this is not a good situation in the long run.

I don’t have many symptoms these days. Just some mild intrusive thoughts occasionally. I think seroquel might work. Not many options when I need something to replace olanzapine sleep action, and the insomnia I am dealing with. The only other thing on the table is nozinan, which is first generation. I read about it but don’t want to try it except as a last resort. I could possibly try risperidone too, but don’t know if it will help sleep enough.

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Thanks @Marian Yes, I’m sure it’s possible. Just need a little luck and hope I make the right moves :slightly_smiling_face:

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Risperdal caused me insomnia, but it’s good in low dose combo with Seroquel

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I don’t want to praise any medication, but I was most thankfull to Seroquel(qutiapine) because that it helped me to get of Zipasidone 160 mg.
Tomorrow I’ll ask my doctor about getting off seroquel and get an increase in Clopixol LAI to 500 mgs every other week. I want to excuse for my unheard behaviour lately but I’m in the midst of a depressions for the first time in my life. So I’m going to suggest the antidepressive Remeron((mirtzapine) for my depression.

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I’m sorry you feel depressed. I’ve done things I’m not proud of, in the midst of depression. Not seen any unheard behaviour of yours. Hope all the med switches will turn out okay for you.

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That’s the only AD I tried, but didn’t like it. I find natural AD’S work for me with no side effects. Like high dose vitamin D(5000IU), or herbs like rhodiola rosea and cat’s claw. Lately I tried oleamide which affects very many receptor systems in the brain, including the cannabinoid system that cbd oil works on. It helps mood and is also good for anxiety.

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I prefer herbs over meds too. But do be careful with those too.

You sound rational about the med change, I trust you make the best choices you can.

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any antipsychotic that have affinity to h1(histamine) receptor will make you sleep. in my personal experience lurasidone (latuda) sedates me at night only because i take it at night and amisulpride(solian) was potent enough to sedates me all day

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I’m guessing I just have to find a natural way to treat these low moods.

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I was supposed to wait a little before trying the switch because I haven’t moved into my new apartment yet, but I’m just so sick of the olanzapine. I have terrible decision making on it, like self destructive and I’m sleeping poorly, especially the last few days.

Even if I have to go back on it, just a few days of relief would do me good. The key is to get sleep with the seroquel. Only one way to find out. My patience is spent.

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Interesting switching strategy, sounds pretty careful and or risk adverse.

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Unfortunately it did not go well. Basically I had two sleepless nights since switching. I took 50mg quetiapine first day, and 75mg second day, but did not respond sleepwise.

My health isn’t so good, so I can’t sustain so much sleeplessness. Going back on olanzapine tonight.

I might have to ask my doctor to be taken off ap’s so I can try out pure sleep meds, reason is they are not willing to give me sleepmeds as long as I am taking ap’s because of interaction risks.

It’s desperate, but I only have poor sleep on olanzapine even at 10mg, and when I try to switch to another med I can’t sleep at all.

I can’t get facetime with a pdoc, my application has been turned down 4 times. I’ll have to work something out with my gp.

50 - 75mg of Seroquel seems really low. They prescribed such a low dose? I think 400mg Seroquel is anti-psychotic level minimum. If they tried you on 400mg, it will probably knock you out for long hours of sleep.

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I can relate to your problem because I take the worlds most sedating typical antipsychotic Clopixol and Seroquel as vil well. I will get terrible insomnia without the Clopixol and there is nothing worse for me than sleepless night as it can even worsen psychosis. So my advice to you is to go back on Olansapine(zyprexa). My mother who is 77 years old is likewise you also on Zyprexa. She jokes and tell me that the zyprexa are here happy pills and I joke back to here and call the Clopixol depo for my happy injection.

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