Multiple antipsychotics at same time?

When I was diagnosed several years ago due to hospitalisation the doctor put me on Abilify, Olanzapine and Seroquel all at once. All daily at mid-high dosage but can’t remember specific numbers

My fellow psychotic people in my support network have all said it’s odd that I was put on all three of those at once so suddenly and I kind of think so too, and none of them helped me personally

What’s everyone else’s experiences, have any of you had to take 2 or more antipsychotics at the same time?

1 Like

That was odd. To put someone on 3 antipsychotics should be a last resort. For some people who are sensitive to drugs it could kill them.

I only took low dose lurasidone and seroquel together for a short while. Didn’t work out. Dangerous side effects in form of chest pains.

1 Like

I take two AP’s - 500mg amisulpride and 5mg haloperidol

I take 1mg of risperidol on top of my fluphenazine because I get irritated and angry if I’m not taking that med once a day. The risperidone helps with the irritability. It’s a small dose though so not too much side effects. It does sound dangerous to be on all those meds at once because of all the different side effects they could potentially have. Would slow down your mind a lot too I would think. Sounds like you either need to change your doctor or tweak your meds a lot.

I’m on Invega Sustenna, Zyprexa, and Clozapine.

I would find a new doctor if I were you.

1 Like

I take two - Ziprasidone and Clozapine, and they work well for me. Everyone is different, and have different experiences. I guess at the time you needed 3.

Literally at the same time or stage over days or the course of your stay?

Had you tried any of these medications individually before?

All at the same time. I wasn’t on meds before being admitted. I’d tried a couple antidepressants before then but never for long (I was a teen and it wasn’t enforced)

I was brought off seroquel after my second admission to a different hospital a few months later, they kept me on olanzapine and abilify until I very unwisely went off them cold turkey (again, teen, not enforced)

I’d maybe give one a try but the thought makes me very nervous tbh. I have a pretty good balance with my current meds and I know it could make that balance even better but scared of it throwing everything off

That’s a bit of a ■■■■■■■ weird move by the doctor. You would really have to speak to them and ask them what they were thinking

Honestly the strangeness of it almost warrants contacting them for an explanation

Fellow new schizophrenics would be better getting advice on the internet. Doctors don’t seem to care and just load you up with whatever gives them the most money. I’d suggest at least drop seroquel

1 Like

Disagree 151515

My last psychiatrist I had wants me on latuda and seroquel.

I disagree.
Seroquel has too many side effects like weight gain , low blood pressure, high risk of diabetes etc .

I’m only on latuda now.

I may try to find another psychiatrist who will work with me.

Geodon and Seroquel work very well for me. Geodon gave me an Akathisia episode but only lasted several hours and has not happened again. I figure I take 40mg Geodon when I get up, then Zoloft a little later, then 40mg Geodon around bedtime, then 400mg Seroquel a little later. This daily operation works well for me.

I don’t know about your country but here in Chile is common to use high doses of various antipsychotics at the same times to “stabilize” psychotic patients and then after some time they reduce the dose to one or two antipsychotics.

I am on low dose amisulpride - clozapin combination. I am very satisfied, I recomend it to everybody with negative and/or cognitive symptoms.

1 Like

After many years of single and double drug typical and atypical antipsychotic therapies, none of which worked for me at all, my pdoc added a third AP to my regimen. And voila! Worked like a charm on all my stubborn symptoms: mood, psychosis, and anxiety. @taiga

1 Like

Hey! Can you please let me know how the amisulpride is working? I’ve heard this is the best of all of them

Happy cake day @Gamma_Fox !

1 Like

It works well for positives and negatives and only side effect I noticed is high prolactin but that doesn’t bother me. I’m on 500mg

1 Like

My personal experience with antipsychotics is that I feel the best I’ve done in years on the two calming meds Clopixol and Seroquel. I know that it’s said that one antipsychotics is the ideally way to treat.psychosis but in most cases two are needed and in rarely occasions tree are needed. Some people need very activating antipsychotics and others need very calming meds likewise me.