My tryptamine level is twice as high from reference range. And my health practitioner dont know how to reduce it… Usually when tryptamine is elevated it causes psychatric ilnesses.
Everybody’s different and it looks like you’ve found the insight into the core of your condition. Try google searching for more natural ways to reduce this chemical. Surely there is a dietary way to help you out. The doc probably just couldn’t think of any meds to help you out.
looks like tryptamine is a wide variety of chemicals. Interesting
The only thing i can do is to know what foods are high in tryptamine so that i can avoid it.
Tryptamine is a trace amine formed from tryptophan decarboxylase. Tryptophan is also the substrate for tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin. The activity of these two enzymes acting on a common substrate will affect neurotransmission by altering tryptamine and serotonin levels. Tryptamine also occurs naturally in fermented foods, and similar to tyramine, consumption by patients treated with monoamine oxidase inhibitors can precipitate hypertensive crisis. Alterations in tryptamine levels are an indicator for dysfunction within tryptophan pathways, and therefore, serotonin-related systems and altered tryptamine levels have been reported in psychiatric conditions, including depression and schizophrenia. High tryptamine may also indicate an increased shunting of tryptophan away from serotonin synthesis. Inflammation due to illness, a factor known to affect tryptophan metabolism, as well as normal sleep, decreases tryptamine levels. Tryptamine is normally metabolized by monoamine oxidase, the same enzyme that metabolizes central nervous system monoamines. Alterations in the activity of monoamine oxidase will result in changes in tryptamine levels. this insight can provide important information regarding the biochemical underpinnings of central nervous system imbalances, monoamine turnover, and the enzymes, cofactors, and other constituents of the monoamine metabolic pathway.
lithium might help
I would say be careful about jumping to any conclusion that there is “One” cause for any mental illness. Generally mental health problems are caused by a number of issues and complex (108 different genes in a recent study) biological and genetic predispositions.
Just as there is rarely one cause, there is likely to be more than one “solution”.
Your case “may” be the rare exception - but I would be careful about jumping to that conclusion without some very solid, scientific evidence.
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-what he said. Correlation does not imply causation. There could be a third, fourth, fifth, up to hundreds of other variables making you have psychiatric illnesses. Basic science. That was on a test on Monday, we were asked why correlation does not imply causation.
My kynurenic acid is at the border of being high
Both of the neurotransmitters that are elevated have someting to do with psychotic ilnesses, unfortunatly there isnt much info on kynurenic acid
I can relate to being fairly certain of the cause of my mental illness too…and yeah there’s not much I can do about it either…I could come forward…I could say “it was a guy named Matt”…but I’m fairly certain I’d end up nailed to some cross in the process…my better sense says “F-it”.
your just going to have to carefully experiment with different treatments till you find the right combo that will help manage it
also for all you know, the “cause” of your tryptamine levels being high, there could be a “cause” for that too. its kind of a merry go round type of thing
I believe our cause of mental illness is in our neurotransmitter, there are 100s of neurotransmitters, unfortunatly there is only few tests can be don, and those few tests doesnt fullfill our mental state.
I am really not sure why my symptoms have improved in the last fifteen years. It could be because of less work stress, better diet, giving up smoking, better social connections (I got married), different medications, day treatment, recovery inc. meetings, extensive reading, avoiding overstimulation, better finances, a safer neighborhood to live in and probably a dozen other ways my life has improved. I can’t tell if my symptoms wouldn’t have improved without these things but I think they helped put me back on an upward spiral rather than a downward one.
The tryptophan may be one big piece of the puzzle but the cure (or at least major improvement) is holistic. The environment, body and mind have a huge number of knobs to tweak (and perhaps even twist a bit).