I’m considering switching from olanzapine to seroquel. Stopping olanzapine 5mg immediatly and starting seroquel the next day. My doctor OK this. I’m just wondering how to go about it when it comes to dose. Last time I tried 50mg was not enough to give me good sleep. maybe 75mg? any thoughts?
No idea but good luck with the switch, hopefully someone else can chime in with thoughts.
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We can’t tell you what dose to take, except to look at the bottle and take it exactly as prescribed.
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When I last switched AP’S my pdoc put me on 5mg Abilify. It wasn’t enough, and he had to up the dose. Be sure to let your doctor know if your symptoms come back. With me, there was some side effect of Abilify he was concerned I could come down with.
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Doctor wants me to take at least 100mg daily when the transition is finished. But I have discretion to try out dosing to see what works. 100 might be just a little bit too much to keep my job. So I might try to stay on 75mg which is equivalent to 5mg olanzapine which I am on now.
I know 200mg seroquel is regarded as minimum dose for sz, but I’m sensitive to ap’s. Maybe I have poor metabolism.
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Good luck @Mr_Hope . I hope it all works out
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Thanks @LilyoftheValley
First hurdle is to get proper sleep. Second hurdle is not relapsing.
I’m optimistic if I get past the first one.
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I can’t take atypical antipsychotics. Seroquel was the worst one. As everyone else says take it as it says on bottle. You’ll be alright. Happy new year.
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Because of sequential binding the dosage at which you get “the therapeutic window (60–80% blockade of central D2 receptors)” for seroquel is grossly sedating.
Ergo the real relevance of this meme
Seroquel makes a good addition if you have sleep issues but not so as a sole agent. Could get okay results if you get no positive symptoms but have still sleep issues at 75mg. It makes sense why they are suggesting you take 100mg, but ultimately you’ll have to feel out the dosage yourself anyway.
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I thought it was 400mg. I’ve always been prescribed 400mg Seroquel minimum.
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I can’t take Seroquel in the morning, it’s really unpleasant. But taking it at night is good for sleep.
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Love that meme lol
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Cool meme.
My thoughts, as a not-doctor who does not know you…
- What is the reason you are not doing cross tapering, slowly decreasing olanzepine and slowly upping seroquel to a level that feels okay for you? It’s what they do here nowadays, to prevent withdrawal effects a bit.
- Starting with 75mg doesn’t sound strange. You could up it or lower it depending on your needs.
- You and only you can feel the discomfort you have, and are willing to accept, from both meds and illness, and the balance between the two. We do not know. I do not believe in standard dosing.
- Maybe you could journal, or even share your journal with someone, to see the development around the switch, and decide to up and down?
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Doc said I didn’t need to taper because I’m already on a low dose, 5mg olanzapine. Also I have tried cross tapering between these drugs before and it has not been pleasant taking both of them at the same time. A lot of headaches and weird sensations in the brain. So I prefer to switch directly.
Yeah, I think 75mg will be what I go for which I will take in the evening. I might take 25mg extra in the morning/afternoon, if I feel I need it. I think this will be my strategy to start out with.
Good idea about journaling. I might try that, at least to a extent.
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