D2 occupancy of Lumateperone (ITI-007)

Here is an article in Nature: https://www.nature.com/articles/s41386-018-0251-1

What I have heard about Lumateperone: It is advertised to be safe and have as the only relevant adverse effect somnolence (in low doses it is an investigational sleep drug). https://www.ecnp.eu/presentationpdfs/71/P.1.g.038.pdf

Correction: The article ist not in Nature (would also have been strange), but in Neuropsychopharmacology (2018).

Im not a big fan of this drug mainly because i dont think it would control my positives, The evidence for its effect for positives is not very good.

good afternoon please tell about this drug. What is known about when it goes on sale?

See here https://www.drugs.com/history/lumateperone.html, which links to https://www.drugs.com/nda/lumateperone_181211.html “The FDA has assigned a Prescription Drug User Fee Act (PDUFA) target action date of September 27, 2019.” https://en.wikipedia.org/wiki/Prescription_Drug_User_Fee_Act

It seems to have as the only relevant adverse effect somnolence, but I don’t know about its effectivity compared with other APs.

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