Clozapine aka clozaril

My nurse practitioner suggested trying clozapine also known as clozaril and I don’t think I will, not because I’d have to get blood work weekly for 6 months and tapper down every 6 month for several years but because my foot STILL isn’t healed but I have diabetes on both sides of my family, my liver isn’t the best and even when I try to drink enough water I tend to almost completely stop drinking water at some point it’s something I struggle with

There’s just to many things that could go wrong and my mom is 100% against me trying it because of the reason I gave above it’s just so many variables I can’t risk it

3 Likes

i have diabetes on one side of family and i was almost underweight when i started clozapine and efter just 6 months my blood sugar was high and i had gained 60 pounds. and it messed with my heart. and other ■■■■. now 13 years later my blood sugar is perfect it was 100 percent the clozapine and also the weight i gained on it.

2 Likes

I just stopped clozapine on March 12 due to the cardiac issues it caused. It was a good med for me mentally but I could no longer handle the QTc prolongation and tachycardia. The cholinergic rebound after quitting it was bad, too, with diarrhea and nausea and insomnia. The insomnia was the worst cuz it made me think about suicide a lot and I felt like I was going crazy. The last 2 days it has improved. If I could avoid the heart issues, tho, I would go back on it cuz I feel it was the best med for my sza symptoms. I’m on Zyprexa now and have been craving carbs so I’m gonna have to watch my diet more closely.

2 Likes

I totally agree with iyou Rellevant weight gain is more an issue for Clozapine than any other drug. I gained 50 pounds in a timespan of 6 months 25 years back in time and I quit it because of severe constipation. Besides of that I suffered under excessive drooling and sedation. My pillow had to get swapped every months because of that. The world’s strongest antipsychotics that comes with the worlds worst side effects.
If nothing works at all then go for Clozapine. I agree on that with no doubt.
The doctors would recommend their children to go on Clozapine if their children became Schizo Affective.
But they sure, damn wouldn’t go on it them selves because all the side effects would become intolerable.

2 Likes

I’ve been on clozapine fifteen years. It was working good until they decided to reduce it due to the risk of fits. I probably would have been better off on olanzapine

1 Like

Been on clozapine for 3-4 years

1 Like

Shelly I was on 600 mg Clozapine by mouth and 300 mg Clopixol LAI every other week and I got psychosis free on that dose.!I got lowered to 400 mg Clozapine and I got psychosis again and was then placed on 600 mg again.
Had I continued to use 600 mg Clozapine ever since I started it I’m sure I had been psychosisfree for 25 years and might have been of the Clopixol for good.
If nothing works then I agree on Clozapine cause that’s the most efficious meds for psychosis.

Maybe I was one of the very unlucky persons who got all the side effects mentioned in the Clozapine leaflet.

1 Like

I’m on clozapine and need to get blood work done once a month. Why do they need you to do it weekly?

1 Like

@PhotoGuy not sure

The longer your on clozapine the less likely the risk. I get bloods done once a month but am unlikely to get problems they are just extra careful

3 Likes

I was on Clozapine. I found a better combination later, but combinations are part fortune, you never know which one will work.

1 Like

Here the first 6 months on clozapine you need to do weekly tests
After 6 months , biweekly

And after 1 year finally it becomes once monthly

1 Like

I’m trying to taper clozapine. Now on 20 mg.

Hopefully, I’ll be on Invega and Wellbutrin only when I move to Spain.

1 Like

Is it hard ?
I mean titrating off?
I’m supposed to be doing the same next month

Currently at 100mg daily for 3-4 months noow and am still ok :crossed_fingers:

1 Like

My voices are a bit louder and I feel a bit more tired during the day because I sleep less deep and fewer hours.

Still planning to go ahead.

1 Like

But you are also on invega?

My only complaint is actually vivid dreams
Like last night I had a dream where I was yelling and I woke up and noticed I was actually yelling in my sleep. Freaky, never had such a thing

1 Like

I also take 12 mg of Invega.

And yes I have vivid dreams every night and wake up several times. I’ve had it since this all started over a decade ago.

1 Like

I regret not trying it sooner

Been saying no to it for years

Apart from constipation and heavy sleep it’s ok

On 450mg a day right now but they may increase it as I have been putting it off

Same bro
I wake up several times a night
It’s been this way for 4-5 months now

I kinda got used to it
At least I can get back to sleep relatively fast

1 Like