Atypicals that work on antagonizing Dopaminergic systems are notorious for causing akathisia. Is there one which is the least evil of them all?
I’ve heard Rexulti is more Seratoninergic than Dopaminergic and hence akathisia is not an issue when taking it?
Any ideas?
Zyprexa is quite unlikely, however it runs a risk of diabetes and weight gain. Clozapine is another alternative you could mention to your pdoc, zyprexa is basically a clone of clozapine
Psychiatrist I think told me seroquel was more sedating than activating. I’m on risperidone which he said was neutral and shouldn’t really sedate or activate and I’ve had no akesthesia so far. Abilify gave me terrible akesthesia right off the bat.
Probably something like Zyprexa since it is so sedating.
I’m on invega. When I was first put on it, my psychiatrist raised the dose really quickly and it caused a lot of akasthesia.
Then he lowered the dose and I got used to 9mg over a long stretch of time.
Then he raised it back up to 12mg and I was more ready for it I suppose because it sisn’t cause the horrible akasthesia this time.
I can’t sing the praises of invega enough, it has really been the drug for me after trying a few others.
Don’t go near abilify if you are worried about akasthesia though.
Seroquel is but it causes a lot of weight gain
I get restless leg syndrome if I take more then 150mg of Seroquel.
Just sayin.
Seroquel and clozapine supposedly cause the least akathisia because they are fast off antipsychotics. They dont occupy the d2 receptor for a long time. They might cause eps but they cause it the least says research
A doc told me clozapine doesn’t cause akathisia, but you need blood test with that one right?
For me personally, Seroquel in doses higher than 150mg make me have to keep getting up and move my legs. It’s an extremely irritating feeling.
Clozapine is a med of last resort only. It was banned once for its blood side effects but put back in use only for people who dont respond to other meds. And supposedly has a list or database where if your white blood cell levels lower you get put on the list and cant take it ever again
Zyprexa, Seroquel, Clozapine causes the least amount of Akathisia.
Abilify is usually Awful when it comes to generating Akathisia.
I don’t have any akathisia on Invega.
Yes @Minnii Invega and Risperdal can cause Akathisia at higher doses but it does not happen with everyone.
I’ve had good luck with Geodon and Seroquel, if that’s any help. Sometimes I think I might be getting a few tremors, though. I hope it’s not Parkinson’s.