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Anyone try a supplement called 5-HTP?


It’s supposed to act like an antidepressant. I’m just wondering if it makes any difference to negative symptoms.

I’ve just ordered this.



Be careful 5 - HTP can trigger manic episodes, especially in SZA and bipolar patients.


I became manic on 5htp.i quit all supplements. Might work out for you.


That’s a form of tryptophan, which metabolises into kynurenic acid, that is hypothesised to be the cause of schizophrenic symptoms.

I wouldn’t recommend it.


This is a precursor to serotonin. Taking 5-HTP is a way to try to raise serotonin levels in the brain. Medicines like Prozac and Zoloft attempt to do the same thing by stopping the body from breaking down the serotonin that’s already there. The medicines work by a “less out” method. 5-HTP works by a “more in” method. More scientific evidence is needed to determine how well it works.


Don’t take it if you’re on an antidepressant, it could cause an excessive build up of serotonin and lead to serotonin syndrome.

“”“Serotonin syndrome (SS) is a group of symptoms that may occur following use of certain serotonergic medications or drugs. The degree of symptoms can range from mild to severe. Symptoms include high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea.”""


I think an acquaintance uses it after having taken MDMA cos that stuff depletes ur serotonin.so u feel depressed.


Made me start to get manic when I took it a long time ago


I tried it. Me too I thought It could help my negatives, but it made me just agitated and anxious as the other antidepressants. But in my illness, I am very anxious at the base so if its not your case, it could help you I guess. I found that its quite active wow, not just a placebo.


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