It is incredible that today’s antipsychotics still apply the same mechanism of action, all with the same mechanism of action. And they’re just based on a drug that they gave to a patient in about 1950, who was paranoid, and was given a drug to lower dopamine.
What all antipsychotics have in common is that they lower dopamine, based on this, they put “antipsychotic” on it. It is more than obvious that the medical treatment is very bad.
An estimated 15% of schizophrenics worldwide commit suicide and it is no surprise.
The 21st century is said to be the century of brain discovery, and I have no doubts about that. I wonder if I will be able to see the new treatments?
Do you know when approximately you will see a new treatment?
I doubt that the pharmaceutical industry wants to come out “a vaccine” to prevent schizophrenia in the future. Because there would be no more business.
probably at the same rate weve been producing stuff… its not magic just takes time for trial and error… i think this stuff is pretty predictable to someone who knows about science and medicine… predicting breakthroughs and that sort of thing
IDK, I got put on prolixen, a first generation drug in 1981. In 1984 I was doing bad and felt like giving up and that I would never get better. My mom told me I had to keep going, that new, better drugs could come out at any time in the future. And sure enough pretty soon 2nd generation drugs came out. They don’t work better but they have less side effects. But the point is that no one knows when more effective AP’s will come out but theoretically, it could be any time. I saw it happen.
I wish they could make new antipsychotics that don’t put on weight indefinitely.
This is one of the main reasons schizophrenics stop their medication.
And the other main reason is that it worsens the negative symptoms of the disease. At least in my case, I feel very ‘’ zombie ‘’. I find it hard to enjoy. I only enjoy eating because the antipsychotic increases my appetite.
Dopamine is the chemical responsible for happiness and pleasure.
As long as the pharmaceutical industry does not start to manufacture antipsychotics that do not lower dopamine, schizophrenics will sooner or later stop taking the medication.
They do, but side effects vary from person to person
When I was on Olanzapine (40mg) I ballooned up to 240lbs.
I switched to 60mg Lurasidone(Latuda) 2-3 years ago and have lost over 80lbs. I am a healthy weight now and my blood test results are immaculate, I am also stable and symptom free. So not all antipsychotics are guaranteed to make you fat, but a lot will, it just sucks that if the only one that works for you has that side effect. Lurasidone hasn’t caused any weight gain, my appetite is the same as it was before I was diagnosed with schizophrenia in 2004.
I feel better than I have in a long time. I’m still not the same person I was before I developed schizophrenia and was put on APs, but I love comedy and laugh my ass off all the time at funny stuff. I also got a job for the first time in 17 years and am doing really well at work.
But it must also be said that each person is a world.
Otherwise there would not be 15% of schizophrenics who commit suicide worldwide.
Even on the drug leaflet it clearly says: ‘’ The mechanism of action is unknown. ‘’
I wonder how they will do in the future to see how the brain works inside, having 100 billion neurons.
I think that for schizophrenia there will be modern treatments but much later than for example for pressure. To give an example.
The drug companies have an incentive to develop new AP drugs. They will be profitable. The typicals cost very little. Haldol costs pennies to make. The expense of the new drugs is worth it, because they come from valuable research on the brain. Also, the typicals are just plain hell to take. They use Haldol to torture mental patients in Russia.
I remember reading in a note that they did that in a hospital in Barcelona in Spain. They put something that was electronic into the brain of a woman with schizophrenia that raised or lowered her dopamine. The woman was hospitalized for decades and was able to go out to live. But the method was somewhat invasive. It was not a chip. What you say makes a lot of sense and it may not be that long before it happens. All side effects of antipsychotics are avoided.
I don’t know. They would probably cure us if they knew how. Pharma might lose money, but society would benefit, as a lot of us would be fit to work again. Workers are in high demand in western and industrial countries.