What happens if you have too little dopamine?

What happens if you have too little dopamine?

Dopamine deficiency can affect your physical and mental health. Many medical conditions are linked to low levels of dopamine, including Parkinson’s disease, restless legs syndrome, depression, schizophrenia and attention deficit hyperactivity disorder (ADHD). Treatments are available to manage these conditions.23 Mar 2022

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Its weird that in Parkinson low dopamine causes psychosis while in sz its the high dopamine, our APs don’t work for Parkinson psychosis:

NUPLAZID is the only medicine approved to treat hallucinations and delusions associated with Parkinson’s disease

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Nuplazid doesn’t work for sz but only for psychosis caused by Parkinson

It’s probably indicating that it’s two separate functions on the brain @san_pedro . It’s not new science but Parkinsons and sz are totally different in outlook and that is what happens with low dopamine like @Aziz has pointed out.

Seriously. Work on your diet and exercise frequently. It leads to way better outcome with sz as the modern research is finding. Keep taking your meds because even though they lack a lot for most we are in the ball park so those dopamine drugs do work for a lot.

If you’ve seen the news on the antidepressants then you’d know that the serotonin isn’t affected as we thought so it wouldn’t be suprising that antipsychotics are the same…It’s not an exact science and we’ve much to learn.

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Ive heard it can be low dopamine too. I believe it could be.

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The positive symptoms are caused by high dopamine in the dorsal striatum of the brain thats proven 100% as meds block dopamine there but there are many theories about the negative symptoms one of which says low dopamine in the frontal cortex of the brain causes them.

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I find other theories about negative symptoms depressing as they can never be fixed, brain structure abnormalities and gray matter/neuron loss but MRIs showed only some sz patients have these.

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low dopamine causes low motivation

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Low dopamine can also cause adhd too apparently

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Dopamine causes psychosis

Also improves negative symptoms

I get restless leg syndrome after I take my morning AP. Not every day buy more often than not.