The benefit of minocycline on negative symptoms in schizophrenia

http://www.isrctn.com/ISRCTN49141214

Scroll down and it says Reason -abandoned.

I guess it wasn’t a success.

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I guess we could contact Bill Deakin (bill.deakin@manchester.ac.uk) to ask for more details.
All in all, I wasn’t putting my hopes on this particular medicine. I am waiting for a genuine treatment against negative symptoms, one that accounts for genetic variability and illness duration and any other factor one can possibly think of. CRISPR sounds like a good plan but not in the near future, the technology might be mature by now but our understanding of the brain is not.

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How is crispr going to help those that already have sz? It seems like it could only prevent sz births by altering dna

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This article gave me hope

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tried minocyclene, did not help

Thx, @Andrey this could be a cure-all, but it’s still early to tell and who knows how soon although that article was optimistic.

We’ve been hearing about this one for years. It seems researchers are beating a dead horse.

Btw, @Andrey for crispr to work u need to know which genes to fix, which for sz there is no single gene as well as hundreds of genes being risk-factors, I think it might be far away from being helpful for sz

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The C-4 gene has been repeatedly implicated in the development of sz. I think I manipulated it with chronic bong hits of the purple haze back when I was in high school. I need Crispr to put it back