Should I switch to Latuda or Saphris?

I’ve been on Geodon for 3 years. I’m currently experiencing paranoia where everyone is judging me or watching me. I also had tardive dyskinesia, but it went away. My mom doesn’t want me to change. My psychiatrist said give it a month and if I’m still experiencing the paranoia he’ll change it. It’s been almost a month and I’m still experiencing paranoia. Do you think it’s a good idea to switch? I’ve been on Abilify, Zyprexa, and Risperdal. They didn’t work
Thanks for any advice

Ive been on Latuda for almost 4 years now. And its been a godsend. Ive tried every atypical antipsychotic there is, plus the last resort Clozaril. And Latuda has given me the best results out of all of them.

I was also on Saphris for a few months. But I had to stop taking it because it gave me insomnia and made me eat ravenously at night. But there’s some good research behind Saphris, and many people benefit from it.

These are just my experiences. Everyone reacts differently to medications. So do your research and discuss the options with your doctor.

Best of luck to you!



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My pdoc is switching me from Risperdal and Seroquel to Latuda. I was on Saphris before and hated it. It was like sucking on an aspirin. I don’t remember it doing much for my symptoms. My pdoc says she had a patient who had been on every med and was still struggling with voices. He went on Latuda and they stopped. Good luck with whatever you decide. I hope the paranoia stops that’s the worst feeling. :sunny:

I’m on Saphris and liking it. It took several months to get used to though. You have to stick with it to get used to the sub-lingual thing. It makes your mouth all tingly and makes things taste off which may help curb your appetite. The only downside I see to it is that I fall asleep within 20 minutes of taking it and sleep about 10-12 hours, so its pretty sedating but no hangover feeling, i wake up clear headed. No voices or paranoia for 4 months, its been a godsend. I recommend trying it

listen to your psychiatrist,if its been a month,then you should try it!i was only on abilify for 4 years and its hell before mirtazapine came to help me out of depression/dark road

I took Latuda for about a month & it seemed to solve all of my problems at first. It was helping me sleep & made me a complete motor-mouth, but it makes my heart & pulse beat way too fast. I’m on Abilify, Remeron, & Nuerontin right now. The Abilify used to make my vision blurry & made my sight weird like I had dyslexia if that makes sense, but I never had that problem before I started taking it. The Abilify quit doing that after it got it my system. It used to make me tremble too, but I cut the MG’s down & it hasn’t had time to get back in my system yet. The Latuda seemed to work good besides racing my heart & pulse, but all meds work different on each person.

My daughter took Saphris and gained a lot of weight. About 80 lbs in six months. She is on Fanapt now and the midnight fridge raids have stopped. She is now able to watch what she eats and the weight is coming off very slowly.

Just want to add that i’ve been on Saphris 7 months and haven’t gained any weight. It must affect everyone differently. I gained 80 on Risperdal.

I take Seroquel with my Geodon, and that helps.

Like @Skims, I also took Saphris. It worked for me very well, but everyone’s different. Most people who stop taking it stop the first, second, or third day, which is ironic because it takes 3-4 days for it to start working. I don’t blame those people because I almost stopped myself, because of the extreme restlessness. But if you can handle those 3-4 days, afterward, no restlessness and it does it’s job. That’s also from reviews of others. I’ve also heard from a couple people that it made them worse in a way, but I’m not sure how long they tried it for. For me, it leveled me off, cut the hyper and psycho-analytical stuff, and just all around calmed me down.


It only takes a few days to work??

Amisulpride and risperidone are two of the strongest antipsychotic to work on positive symptoms

Check this report to find out which antipsychotic might suits you best

I agree, after Clozapine, Risperdal is best. That’s from my own experience with 4 antipsychotics. I had the least positive symptoms with 4mg Risperdal. I still have some but they don’t bother me. I am sure Clozapine get rid of them but I got used to them.

Latuda was okay. Saphris tasted like aspirin.

Lions mane can cure you. I’m telling you. It can do that. It really can. amyloban 3399 specifically. I’m telling you this. I mean it. I know. It can. It really can. All other supplements are 90% placebo. This is the real deal.

I’m on Latuda it seems to be working well.

I don’t know if it will help with paranoia, but I was able to lose weight on it, and it might have had some positive effect on my depression.

Hard to say on that, I was mostly paying attention to the changes I would watch for, for negative symptoms and positive symptoms.

Did it help with apathy and avolition?
I tried it for a year but it didn’t help, just akathisia and nausea. I wonder what happens if I take it again but my dr doesn’t want to change my meds anymore, he told me to stop asking for a med change.

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Sounds like my doctor :smile: