Should I Reduce Olanzapine

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Hi, I’ve had 3 psychotic episodes. Before the last one I was stable 5mg Olanzapine for nearly two years and had little side effects. I then came off medication and relapsed about 5 months later. I then had a 4 month long psychotic episode without antipsychotics. I was then sectioned and put back on Olanzapine 15mg and regained my insight and got better.

15 months on and I am now on 10mg Olanzapine and without psychotic symptoms. But I lack labido and am struggling with exercise. Hardly making any gains even though I run regularly and put a lot of effort in I barely see any improvement.

I am considering reducing my dose to 7.5mg olanzapine of my own accord but am concerned about relapsing again even though all my episodes have been while off of antipsychotics.

I just looking for that little bit more from being on a lower dose. Hoping my sex drive will improve and physical fitness too. Also I work full time which I find tiring and am hoping a reduction will give me that little bit extra. But I am scared of risking a relapse.

Any opinions or advice would be appreciated?

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My advice is talk to and involve your psychiatrist in all of this.

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I would do but they think I’m on 12.5mg but actually been on 10mg since January. Only see them twice a year at most

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Hows your weight?

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I’m about 14 pounds overweight, have lost about 21 pounds over the last few months as been on Mounjaro. Was nearly obese before then

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Im on Olanzapine too, 5 mg a night. I need to lose 70 pounds though.

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How did you get down to 5mg. Did you do it with the psychiatrist or on your own?

Used to be on 5 mg and would love to be that low again.

scared to make the step down to 7.5mg on my own.

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I don’t recommend you do this on your own. If you talk to the doc and see what they say and they are the best to give advise like this. I was able to go from 15mg to 10mg to 5mg abilify but I did it with consent from the pdoc

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How long did you wait between dropping doses?

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Around 3 years to get to 10 and then about two years to get to 5mg

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