If you combine the STAT CRISPR article, with Stachowiak’s findings of the INFS (FBGF1 Signalling Pathway) as the central guiding mechanism behind the brain malformation that leads to schizophrenia, then you’ve got yourself a roadmap for the future of a cure.
Like Twinklestars says, this could take decades - but by that time medical advancements will have reached a stage where 60 really would be the new 20, so we’re all be partying with a big laugh on our faces. 
It says the pre frontal has less but the subcortical is better in sz. But no one knows what the subcortical is used for. And how then if it’s genetic would it explain varying severity in patients. Also there is more spiritualist theorys that say mind actually exists outside the body.
When are we getting cured…!!! Do u guys have time line…!!!
Far Cry - it’s gonna take a long time. They have to do a lot of tests, comply with laws and regulations, a lot of hoops to overcome regarding potential safety issues/cancerous tumors, and then they have to solve dozens if not hundreds of different problems, like vector delivery, etc. I would say no sooner than 15 years from now, if not later. In the meantime - stay healthy, so you’re ready when the time comes. 
15 years is a lot…!!! Lets be positive …!!! God will bless us…!!!
It’s not a cure but more like a prevention of the disease for future children.
But when you start to edit DNA the thing is, does that affect anything else and is that necessarily something you want?
I think it will alter ur whole characteristics…!!! If u are introvert it may be changed U in to extrovert…!! So its bit unethical…!!! Fu ck man this is so complex…!!!
It is but it’s nothing new.
If sz research will be well funded by rich or billionaire people they(scientist) can reach to the conclusion and they will unravel the root cause of sz… only then better medication is possible…!!! Holy cow…!!!
May it happens soon…!!! What do u think arturo…!!
I sent the article’s to my friend who is also in the neuroscience field (although a different section. I just asked her to tell me what she could) and she’s told me that what the articles explain is nothing new. They discovered that the migration of stem cells and immature brain cells normal migration is disrupted in schizophrenia which is why it occurs later in life. Normally the cells migrate through different layers but the thing that is new in this paper is that they discovered the gene that is doing this and disrupting the normal migration. So it’s why it appears to be a “degenerative” disease, but it’s actually we are taking a longer time to develop fully while everyone else (the normies) are already ahead of us.
I don’t know if they will have anything for us already with the disease but I think that brings us very close to the prevention of the disease to newborn infants.
I know they will find its preventive majors for the infant…!!! What about people already suffering from it … do we get effective treatment in our life time…!!!
From what I’ve seen I can’t tell. But maybe there will be someone who will look at all the collective data soon and start to draw conclusions that can then be tested and there might be something for us there.
Thanks my best friend arturo… i just want to be hopeful…!!
Arturo, thanks for your reply - however the faulty migration happens already in the uterus and people suffering from Simple Schizophrenia have symptoms from childhood - I know this because I’ve had negative symptoms since I can remember.
And these findings are new because like you said, they’ve discovered that it’s the INFS genetic pathway that is causing the neuronal disruption, which means they can alter that via gene therapy and allow the stem cells to differentiate properly.
And yes, the latest article does focus on preventing the disease from happening in the first place, but that is probably because they don’t know how to reverse the malformation of the brain once it’s happened. The other article about CRISPR CAS9 however states that the disease can be reversed once they’ve figured out the kinks and now it’s safe. It’s obviously not gonna happen in the next 5 years, but decades down the line.
Yep that’s what I was saying. You’re right.
I did not read the article about CRISPR but from what I know is that CRISPR is just focusing mainly on prevention of diseases because altering a person’s DNA during life can have terrible consequences while doing it as a “design” for babies is more safe because they can organize things to their liking before anything actually happens. And yeah it’s hard to reverse a disease like schizophrenia once the thing has altered your brain.
I completely agree with you Arturo, genetic editing is extremely dangerous and risky, and I also find it difficult to comprehend how they are going to reverse development that has already happened. If you read about minor physical anomolies in schizophrenia you’ll find that schizophrenia is not just a mental ilness, it’s actually a cranio-facial developmental process gone wrong. That’s why many schizophrenics have elongated faces, crooked nose, and asymmetric facial features and bone structure - simply put, the cells that form our heads have not developed properly, with schizophrenia being just one outcome of that process.
So the complications are extreme - but they say that science is advancing faster than ever in history and that makes me cautiously optimistic.
Do try and read the CRISPR article, it’s interesting. 
They have found that they can edit genes that affect brain development in adult mice and actually correct brain development, in adulthood.
I think it may be easier and more complete in newborns or in utero, but the thing is, genes provide the instructions for development. If they can be turned back on (in a corrected format) critical periods can be restarted, and rewiring can occur.
I think it will be clearer that this is possible after they first cure children or adults with fragile X and Rett’s.
This is all good news!
It really is.
I think genetic treatment for Fragile X and Rett’s are also a decade or more out though.
I hope schizophrenia gets cured one day, and the sooner the better.
I for one believe that we should be able to use the tools of genetic engineering for everyone who wants
them, and not only for curing diseases but also for the purpose of enhancement.