Jimbob as far as I recall youre on Depixol and 400 mg Seroquel. And as you know am I on the sister drug to Depixol namely Clopixol with 600 mg Seroquel by mouth. In the Long run I must say that Seroquel has really calmed me a load and all Thise irretating states of mind have perrished. Surely do Seroquel work for hard to treat psychosis. And yes thanks to the ols and Seroquel I now finally sleep 13 hours after staying awake for only 32 hours. Its not worth it to get slim if you must pay for it with your peace of mind. Im sure you found simular benefit from Depixol with Seroquel.