This is more news on the issue of how there is some (not a huge amount) of gray matter (brain area) loss in psychosis and schizophrenia. Its why medication that helps people avoid relapses may be a very helpful thing.
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Young people at clinical high risk (CHR) who progress to full psychosis have increased reductions in prefrontal gray matter that may be driven by neuroinflammation, new research suggests.
The study also showed that this cortical loss, which was more pronounced in those whose prodromal symptoms were of shorter duration, was inversely associated with plasma levels of proinflammatory cytokines, suggesting the presence of systemic neuroinflammation. Importantly, the investigators note, the tissue loss was not accounted for by exposure to antipsychotic medications.
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