http://schizophrenia.com/?p=692
this article says that gray matter loss in the brain is due to psychosis, the neuroinflammation, NOT due to antipsychotics.
this is because they showed that people who were undergoing psychosis had huge neuroinflammatory markers in their brain, highly predictive of gray matter loss, during a time that they were NOT on an antipsychotic…interesting.
HOWEVER, it also states that experiments on monkeys have shown gray matter loss in monkeys who have been given antipsychotics, compared to controls
so to me, the article seems to be not very logical. because yes psychosis seemed to cause gray matter loss, BUT so did the antipsychotics in monkeys. so it seems like antipsychotics can INDEED ALSO cause gray matter loss, unlike the title of this article suggests.
very confusing. just mentioning this because I was wondering out of curiosity what causes more gray matter loss, antipsychotic or psychosis.