If you drink to much coffee you can warsh out your meds.....Fact or Fiction

[TheGreatestDrZen]

[everhopeful]

From the web:

Second-Generation Antipsychotics

Second-generation antipsychotics that are not metabolized by CYP1A2 should not be affected by either smoking or caffeine. Thus, smoking or caffeine intake should not influence dosing of aripiprazole (Abilify) and risperidone (Risperdal) (the metabolism of both depends on CYP2D6 and CYP3A4) (Prior and Baker, 2003; Swainston Harrison and Perry, 2004), quetiapine (Seroquel) (mainly metabolized by CYP3A4), and ziprasidone (Geodon) (mainly metabolized by an aldehyde oxidase and CYP3A4) (Prior and Baker, 2003). On the other hand, the metabolism of clozapine (Clozaril) and olanzapine (Zyprexa) is mainly dependent on CYP1A2 and UGTs, and hence their levels are affected by smoking and

http://www.psychiatrictimes.com/articles/coffee-cigarettes-and-meds-what-are-metabolic-effects

[cbbrown]

I’ve never noticed a difference in my meds after drinking coffee, even the Haldol. The only thing that happens is i’m more awake when I drink it.