My pdoc explained that emotionally I and my siblings had a different set of parents. They were psychotic to me but ok with my brother and sister. Which would make me believe there is nothing genetic about it. Just something about me and bringing me into the world that tipped them over the edge. My tough luck but I’m learning to understand the paralyzing jealousy I felt as a child. 
Me too no one in my family has SZ.
I learned in biology classes that inactive genes can be transfered and then activated in the offspring.
In other words, both or one of your parents have inactive SZ genes that were activated in you. Or your parents could both have complementary SZ genes that end up activated when present together in you. SZ is mostly a genetic disease, 80%.
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Hey ! That’s exactly what happened in my family too.
But if schizophrenia was 100% genetic then both identical twins would get it and not just one. And that doesn’t happen.
Nobody knows what causes schizophrenia.
My brother also has it. He is much worse off than me. But he ia also a child abuser, so I imagine he finds the guilt hard to live with, and that factors into his ability to cope with schizophrenia.
Mine was brought on by external stress.
It’s a complicated issue. I’ve read there are many genetic abnormalities that contribute but its also an issue of how these interact with the environment and many people related to those with sz who don’t have sz themselves have some related phenomenon.
I’ve seen a few cases on the internet of identical twins where one develops schizophrenia and the other does not.
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for me, it’s the envorment + life experiences which caused it. It is both far more complexed than it seems, yet so simple when one understood what happened, what caused it. It’s all very inter-linked.
I don’t think stress alone causes SZ.
Its when you have a genetic predisposition and you add stress or drugs like weed to it that SZ becomes activated. Genetic severity is what determines prognosis.
That’s what I learned in my university psychology courses. A genetic predisposition precedes environmental stress to cause mental illness.
I heard even cigarette smoking can cause sz.
No lol That’s completely false, where did you hear this?
Can’t remember - but it was said to only be true of some. Where did you get the idea that that couldn’t possibly be true?
Because there is no statistical relationship between smokers and SZ. Smokers get SZ at the same % as non-smokers. If smoking was really causing SZ like weed, the government would put a warning on cigarettes boxes about SZ like weed.
Here in Quebec weed (Marijuana) is legal and on the box it says “Weed can cause and worsen schizpohrenia”. I would have posted a picture here but I stopped smoking weed last year.
Why do blonde parents have one blond haired kid and one black haired kid? That’s genetics. My sisters are outgoing, normal people with good jobs and friends. I’m nothing like them or my parents.
Sz can be passed down, but sometimes it is not to do with a family history and it just happens.
Oh, a genetics question! Here’s what I know so far.
Usually the variants of a person with a genetic disorder get divided into three categories: pathogenic, likely pathogenic, VUS (also known as “variants of uncertain significance”), and benign/likely benign.
And genetic mode of inheritance is: x-linked, recessive, dominant
Okay. So we do not know what kind of mode of inheritance is involved with the inheritance of schizophrenia. We do not know if it is a recessive inheritance or a dominant inheritance.
A recessive inheritance means that both parents carry the gene, and dominant means one parent has the gene that will cause schizophrenia.
So far, we have no idea what mode of inheritance causes schizophrenia. For people who have no members with sz, it may mean that the mode is recessive. For people who have brothers/sisters with sz, it may mean that the mode is dominant.
It’s like central core disease caused by the RYR1 gene- the disease can be caused both recessive and dominant mode of inheritance. So, either way the inheritance can work both ways.
The short answer is: we don’t know the exact patterns of inheritance, nor we know which variants are pathogenic. That would be up to the hands of researchers.
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How the hell are you this smart and so sad @anon10648258 ?
Thanks @anon57786250 - I just searched the heck out of genetics because I have a genetic disorder.
I don’t know, I’m stuck in the mindset of “I’m schizophrenic, and therefore nothing of my worth or intelligence matters because the society hates me” thing. I’m working on it.
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Good stuff. 1515151
Thanks! 15151515
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