Deplin (L-Methylfolate) for Depression

I am currently experiencing pretty intense depression, have been really for 2 months or so now.

Because I am a Rapid Cycler and go through having Mixed Episodes of Mania and Depression frequently, I cannot take Antidepressants as they will quickly switch me over to Mania.

My psychiatrist suggested I try taking Deplin to treat my Depression, its the brand name for L- Methylfolate - A Vitamin that helps improve Mood.

She prescribed me 15 mg - thats a lot of Folate, and it is FDA approved as a Medical Food to augment antidepressants in treating Depression.

It shouldnt make me Manic and I plan on taking it when she comes back from vacation, after the Holidays.

My Sister in Law takes L-Methylfolate, and it improves her Mood - Hopefully it will be a safer alternative to Antidepressants.

http://www.deplin.com/

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http://m.iherb.com/Thorne-Research-5-MTHF-5-mg-60-Veggie-Caps/38045

Edit: from what I can gather this is the same thing, but without a prescription.

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CONCLUSIONS:

RESULTS show that in a naturalistic setting, patients managed with l-methylfolate achieved statistically significant improvements in self-reported depression symptoms and functioning and greater satisfaction with their medication treatment.

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http://www.healingwell.com/community/default.aspx?f=19&m=1394530&p=2

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Yeah, I’m concerned of the potential of it causing Mania.

I may ask my pdoc to prescribe me the lower dose of 7.5mg of Deplin - just to see how I react to it at first, then go up to the 15mg dose if all goes well.

I am highly sensitive to meds.