Commonly Used Antihypertensive Drugs In The Treatment Of Schizophrenia Or Dementia? Let’s Talk About Kynurenic Acid

[twinklestars]

Why are amino acids not being tested in ultra high risk or first episode patients?

Or have they already been? I don’t expect an answer here really, just putting it out to the internet. (These forums may be read even without having a login.) “Recent studies have suggested that increase of brain KYNA levels is involved in psychiatric disorders such as schizophrenia and depression. KYNA-producing enzymes have broad substrate specificity for amino acids, and brain uptake of kynurenine (KYN), the immediate precursor of KYNA, is via large neutral amino acid transporters.” “Ten out of 19 amino acids (specifically, leucine, isoleucine, phenylalanine, methionine, tyrosine, alanine, cysteine, glutamine, glutamate, and aspartate) significantly reduced KYNA formation.” https://w…