Green tea extracts connected to a large proportion of supplement-related liver damage.
Paging @everhopeful
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I don’t think green tea extract (GTE) is the same as L-theanine. Let me do some research… Cuz I’m worried now.
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It didn’t do me any good that’s for sure. It irritated my bladder and had me peeing every 5 seconds.
Well, GTE is basically green tea leaves in supplement form. L-theanine is a standalone ingredient. A green tea extract-extract if you like.
It looks like L-theanine is in the clear though.
https://livertox.nih.gov/GreenTea.htm
Mechanism of Injury
Preclinical and human data implicate the catechin component of green tea as the culprit of hepatotoxicity. Approximately 10% of the green tea extract is composed of catechins; of these, epigallocatechin-3-gallate (EGCG) is present in highest concentration. There is great variability in the concentration of green tea extract, EGCG and other components among marketed products, which may explain while some products have been implicated in hepatotoxicity. Exposure of rat hepatocytes to EGCG has been shown to induce mitochondrial toxicity and generation of reactive oxygen species. The association of liver injury with higher doses of green tea (as in extracts) suggests a component of direct hepatotoxicity, perhaps in the context of some degree of host susceptibility exacerbated by environmental features such as obesity, fasting or glutathionine depletion.
That link also says
Liver injury typically arises within 3 months, with latency to onset of symptoms ranging from 10 days to 7 months
I’ve been using l-theanine for years.
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Hey, if that’s true, @everhopeful, that’s good news. Thanks for looking into it.
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My l theanine isn’t made from tea. I forgot what it’s made from. But I thought that was weird.
I’m Leary using certain supplements.
I like to stick to EPA Fish oil.
I use prescription strength Vascepa
I also take extra Vitamin D3 and a Multi Vitamin.
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