Schizophrenia.com

Broccoli sprout compound may restore brain chemistry imbalance linked to schizophrenia

#1
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#2

Oh cool! I visited an “alternative” gyneacologist once for my premenstrual psychosis and depression, on my own initiative. She prescribed broccoli sprout pills. No idea if it is the same.

I was sceptical, thinking: broccoli?? Really? And i kind of forgot to take it. :confused:

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#3

I love those on my sandwiches. I guess I should eat more of them.

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#4

I would like to ask my pharmacist if he has brussel sprouts on his shelf! :smiley:

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#5

Iv tried like 20+ supplements with no luck, Its temping to try this but it prob wont help.

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#6

Sounds too good to be true!

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#7

I try to eat plenty of broccoli and spinach.
They are super foods.

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#8

Moderate Interaction

Be cautious with this combination

!

  • Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with SULFORAPHANE Some medications are changed and broken down by the liver.
    Sulforaphane might decrease how quickly the liver breaks down some medications. Taking sulforaphane along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking sulforaphane talk to your healthcare provider if you take any medications that are changed by the liver.
    Some medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.
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#9

Weird. I’ve found out I had a broccoli intolerance a couple of years ago, so have stopped eating it and other foods like cauliflower. I also developed schizophrenia in the past year. Sure it’s not related, but whatever. Hopefully I can absorb this supplement without effect.

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#10

There are several trials on clinicaltrials.gov on sulforaphane.

NCT02810964 is a double blind placebo controlled trial on people with schizophrenia who are on medication. The trial is supposed to end in July 2019. Hopefully they will publish their results, if they are going to do so, we might have an idea within a year or so. Both whether it’s helpful and whether there are any safety concerns with meds.

NCT02880462 is also testing it as an add-on, but since they have been in “not yet recruiting” status since 2016, I wouldn’t count on ever seeing data from them.

NCT03932136 is a brand new study on clinical high risk people. That is supposed to be complete at the end of 2020.

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#11
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#12

Would be nice if the research did allow for antipsychotic reduction in conjuction with sulforaphane, although this study from 2015 seems to indicate that only cognitive symptoms are affected.

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#13

I gave in and orded some, should arrive in a few days. hopefully this isnt another one that does nothing.

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#14

I’m gonna give it a shot too. Just out of curiosity which brand did you go with?

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#15

Just got one that was local, piping rock.