There are some strong links between having a family member with schizophrenia and going on to develop it. If you have a close family member with schizophrenia, your chances of developing it increase from 1% to 10%. If both your parents have it, your risk increases to 50%. Of course, not everyone with a close family member who has schizophrenia will develop it.
The genetic components of schizophrenia are still being studied and researchers don’t have a complete picture at this time. One theory is that a microdeletion in chromosome 22 (22q11) may contribute to the development of schizophrenia.