Amisulpride - Tapering off!

DX'd - Sz/SzA
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Hey guys its Joseph, I’m 34 yo
I’m taking an antipsychotic (Solian/Amisulpride) for 4.7 years.
(current dose : 225mg)

After a long research I’ve came to the conclusion that there’s not enough information about anyone who tapered off Amisulpride… but it may be because it’s a less common med.

I was reading about the mechanism of Amisulpride, it appears to be block dopamine as in the term ‘dopamine antagonist’ from 200/400mg and above, but acts as dopamine agonist in low doses. for example: in 100mg it’s still blocks dopamine and simultaneously facilitates dopamine release.

-I don’t ‘get’ any of those clinical definitions. perhaps it means I will just be more vulnerable to psychosis?

today, after I’d CT in the past, I’m willing to try the 10% reduction technique.

So, will it be wise to make 10%-5% reductions each month 'till I’m down to 0mg?
or I need to consider to switch AP to give some ease on the withdrawal process?
– any open minded thoughts are welcome.–

What can you recommend in general?

Thanks in advance
J

1 Like
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Welcome @ssoy_87

If you find yourself in need of help, just tag a moderator. Type the @ symbol, then our names

@anon4362788 , @Ninjastar , @Moonbeam, @rogueone, and @Bowens

Enjoy your stay with us!

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Its not recommended to taper off your meds on your own. You need a Dr. I fall in this trap sometimes too then regret it. I stopped my meds on my own and ended up in the hospital.

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Thank you Bowens!

Aziz, how did you understand from my words I’m not doing it with my doctor’s approval?
I have a variety of safety nets including my doctor.
I’ve asked for specific answers, not this.

feel free to leave Aziz if it’s uncomfortable to you. Actually you know what? You’re making me uncomfortable so please… around this thread I dont like getting these kind of comments so it’s probably for the best for you just leave

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Because you never mention a doctor.

You’re asking a bunch of patients their advice on tapering down.

If you’d talked to your doctor, they might have told you how to do it.

I can see where @anon67051439 would make the assumption.

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I didn’t mention a lot of stuff, that’s where you can ask and not presume

You too can leave if you want… Im not here to argue. I have better things in life.

I’m writing to moderators only. Unless anybody else has an open minded opinion or he could answer my questions from experience

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Btw doctors don’t know a lot of withdrawal, they taper you off in weeks and you get wd symptoms… so it seems you have a lot to learn

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I am 34, and on 800mg. My goal is to get down to 400mg a day…

Like you I have no doctor helping me

Think the 10% reaction is advised with this med like many others

I am grateful for Amisulpride, as it stopped me having to go on Clozapine

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Good luck on your way to 400mg, I’ve been on 800 too

I actually HAVE a doctor who’s willing to help, but he’s there only so I can get the prescriptions from him

Thank you

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I take 400mg amisulpride. It’s my best dose, but sometimes I went to 600 or even down to 200. Anything lower than 200 and I got ill. I love this med and have taken it for eight years amongst others.

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