Hi, I am a psychiatric patient diagnosed with schizoaffective disorder, I have just recently found something that helps me alot, it is the pain-killer aspirin! Apparently it is a COX-2 inhibitor and is currently being investigated as an experimental treatment for schizophrenia. There have been numerous times when I was in severe mental distress and I took 2 Alka-Seltzer tablets in a glass of water and I made a miraculous recovery within about an hour and 1/2 and was fine for the rest of the day! It definently has an effect! Apparently aspirin can cause stomach irritation and bleeding but Alka-Seltzer is much less likely to cause this than pills, I have been taking 1 Alka-Seltzer per day for about a week and I am fine.
I took baby Aspirin for years for blood thinning properties. No effect. Also use a lot of Alka Selzter for indigestion. No effect on positive or negative symptoms, either.
Yes, i use aspirin daily, it’s no miracle but it absolutely helps me.
The theory behind aspirin as an add on medication, is that depression and SZ causes inflammation of the brain, and aspirin reduce the inflammation.