I had severe fatigue and intense agitation from my Amisulpride. These feelings of fatigue and agitation made me very low productive in doing intelligent work such as reading and writing. I am now trying the combination of Vitamin B12, citicoline, and grape seeds. I got headaches from citicoline and got extreme dizziness from grape seeds before. But I don’t want to give up. Now I take 1/4 capsule of citicoline and 1/2 capsule of grape seeds each day. So far so good as the feeling of fatigue was almost gone and the agitation mitigated. Recently I could sit still reading for longer time. Hopefully the half dose of grape seeds will not give me dizziness in the end. Last time I got a severe dizziness after taking grape seeds continuousl for 2 weeks.
I’ve never thought of taking supplements for my chronic fatigue so I’m not so informed about them.
What I do is to maintain my activity levels, meaning that I do pace myself although I try not to rest all day. Plus, physical exercise. Though I don’t think my fatigue is muscular but neurological, I think it helps.
One more thing is that I’m reaching 40 next year and I think age has also come into play. So physical exercise becomes even more important.
It’s thought that chronic fatigue may be due, in part, to a dysfunction of our mitochondria. Mitochondria are the site of energy production for our cells, so it makes sense. Some supplements to look into would be CoQ10, L-carnitine, and B vitamins. Definitely look for a water and fat-soluble form of CoQ10 for better absorption.
I loved CoQ10 the one time I took it. I had so much energy. Then I read up on the drug interactions it had. It interacted with my Propranolol so I couldn’t take it anymore. I wish I could take it though. I’m with ya @kgkc465
There is evidence that Propranolol and other beta-blockers can lower CoQ10 levels, but I’ve never heard of CoQ10 having a negative impact on beta-blockers.
U of Maryland has an article on it here: umm.edu/ health/medical/altmed/supplement-interaction/possible-interactions-with-coenzyme-q10. (I put a space after /edu b/c I can’t post links).
You should of course check with your prescribing doc to be sure!