"According to researchers, reductions in stress, preventing drug use, and proactive cognitive support, as well as the development of targeted pharmacologic interventions, are all currently being explored as ways to mitigate schizophrenia.
"According to one researcher, for primary prevention and secondary interventions, particularly in those in whom a risk for schizophrenia already has been identified, reducing stress, enhancing cognitive abilities, and preventing drug use was found to be essential.
"According to researchers, higher levels of brain glutamate in adolescents correlated with more schizotypal symptoms, leading investigators to consider that there might be a problem with cortical glutaminergic regulation.
"Recent discoveries in genetics have shown how several mental illnesses—such as autism, bipolar disorder and ADHD—overlap, but the way in which they manifest is determined by how one’s genes are either triggered or influenced by the environment or by neurochemical influences, according to researchers.
“Depletion of gray matter in the brain occurs in adolescence, both preceding and during schizophrenia’s prodromal phase, particularly in boys. Also, a decrease in the brain’s plasticity because of exaggerated synaptic pruning by the adolescent brain, an otherwise normal function, has been cited as a risk factor for schizophrenia. Additionally, research into disruptions of the adolescent’s maturing stress response system has shown that, for some, prolonged periods of stress can lead to an imbalance of cortical cognitive control.”