“These data suggest that stem cell-derived interneuron transplants may represent a novel therapeutic strategy for schizophrenia.”
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NewHope
February 27, 2018, 6:29pm
2
its same 2013 research on rodents. same dr lodge.They need to start doing this in humans. Would love to see cure instead of treatment.
Mol Psychiatry. Author manuscript; available in PMC 2017 Sep 25.
Published in final edited form as:
Mol Psychiatry. 2017 Oct; 22(10): 1492–1501.
Published online 2016 Aug 2. doi: 10.1038/mp.2016.121
Thats the info from this article. It took them 3-4yrs to publish the research is what u are saying? Regardless 4 years later and nothing new has come out. WTF!!
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NewHope
February 27, 2018, 6:42pm
4
unfortunately yes. do not know why it took so long to publish here. May be it got published else where earlier. do not know.
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NewHope
February 27, 2018, 6:47pm
5
he has published many papers on the research it seems . This link is from the same page that you provided:
JJ Donegan and DJ Lodge,
Brain research , 2017 15 01
Schizophrenia is a devastating psychiatric disorder characterized by positive, negative and cognitive symptoms. While aberrant dopamine system function is typically associated with the positive symptoms of the disease, it is thought that this is secondary to pathology in afferent regions. Indeed, schizophrenia patients show dysregulated activity in the hippocampus and prefrontal cortex, two regions known to regulate dopamine neuron activity. These deficits in hippocampal and prefrontal cortical function are thought to result, in part, from reductions in inhibitory interneuron function in these brain regions. Therefore, it has been hypothesized that restoring interneuron function in the hippocampus and/or prefrontal cortex may be an effective treatment strategy for schizophrenia. In this article, we will discuss the evidence for interneuron pathology in schizophrenia and review recent advances in our understanding of interneuron development. Finally, we will explore how these advances have allowed us to test the therapeutic value of interneuron transplants in multiple preclinical models of schizophrenia. This article is part of a Special Issue entitled SI:StemsCellsinPsychiatry.
No wonder we are far away from getting cured. 4 yrs for one single discovery. It looks like its a game of publishing papers but not finding a cure. Retards, all of 'em!! This has me even more depressed.
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NewHope
February 27, 2018, 6:54pm
7
do not loose hope bro. He did his part. some body else somewhere would have picked up from he left and we would hear from him hopefully soon.
NewHope
February 27, 2018, 6:55pm
8
also we do not know if he is doing some other work as well which has not been successful and hence not published yet.
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