Stanford scientists solve secret of nerve cells marking a form of schizophrenia

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Hrm. Natal CRISPR therapy for the missing code. Perhaps a safeguard placed in utero? Could help save a lot of people from suffering.

But then again I wouldn’t know the side effects of those kind of human trials, and pinpointing the efficacy would take decades of research on trial pools.

Still, it’s some hope we could find the full cause. Good one EH.

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Yep genes are the main and root cause of schizophrenia. They’re hard to study though.

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I think I have this type. They have panic attacks too. So do I. Says Seroquel, Zyprexa and clozapine? Work best. Not sure about clozapine. The one that causes agranulocytocis.

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I think my schizophrenia type is predominantly negative symptoms like it feels like I got ■■■■■■■ dementia half the time and it progresses even with medication. It could be. I don’t hallucinate or hear voices it doesn’t happen at all. I just have the negative cognitive effects, negative symptoms, and delusions. That’s it. I got mood swings. So I think it’s more schizo-affective disorder. I also drink tons of energy drinks every day so nobody including myself really can tell what I have…

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Why they do not respect the fact that ,diagnosis the symptoms of sz as a biological symptoms by the current scientific tools are remain impossible task until now,while
it is supposed that,they must understand that it is very hard to find a biological cause (s) for a symptoms that cannot be diagnosed as A biological symptoms !

Do you need us to accept that,anything that happens in the brain can be considered as a possible biological cause (s) for a symptoms that cannot be diagnosed as a biological symptoms ?

what happens on all viewed researches is a repetition of the next attempt;
Observing one / more of a cognitive phenomena,chemical substance or functional process that occur in the brain,then explain them in a way that bring them closer to the context of the agreed meaning related to the diagnosed symptoms

Then trying to find a casual relationship between the observed material and creating (developed) the psychological /mental behavioral symptoms of sz .
While finding a causal relationship between the observed material and the creation of a whole central health condition be called schizophrenia remain a mission impossible ,because the absence of actual knowledge which be needed to determine the nature of the sz’s nature itself

Very interesting study. Glad to see that some data are accumulating. Even if in the end this particular piece of data will not be found to relate to SZ, it will surely serve as a piece of the general puzzle, helping further research.

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I would be very glad to see a cure for schizophrenia, and it is even possible that I may personally
benefit from such a development.

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It is just an empirical theories,through which a casual relationship are investigated for anatomical,chemical or functional observations (not counted numerically) that theoretically assume responsibility for creating the mental / behavioral symptoms of a condition be called schizophrenia

While it is ignored to delve into the creation of a whole central health condition called sz,because its essential nature is unknown to the investigator

So,they searching about a change in the cells of some areas of the brain,defective gene(s),one or more of a chemical substance that are secreted into the brain,one of the variable that can occur in the higher cognitive processes or any change that occur in the components of the immune system

The experimental theory always suggests that anything of the above is ontologically precedes the mental /behavioral and emotional symptoms and causes them functionally,and this is a repeated error that does not explain itself or anything from the above

In fact,the scientific research has seeks to find an effect of a chemical substance that can induces a symptom , to be appeared as a similar to a symptom of sz -nothing more,
and they take this as an evidence to creation the sz condition or its symptoms all !

While all symptoms of sz cannot be taken as an evidence for the sz health condition ,because the things be called hallucinations is the ONLY evidence for the condition be called sz ,
And the hallucinations in nature is not a symptom of sz condition or any other at all ,because it is forming the basic structure of the whole condition be called schizophrenia ,and this means that the hallucination is the whole heath condition for the condition be called sz

And all diagnostic symptoms are the end result of the hallucination’s effect on the pathways of higher mental processes ,it is the actual root origin of the symptoms and be considered the existence cause for the symptoms OR the final cause of the symptoms

SO,symptoms of sz whatever way it is written or be understood ,they have no casual relationship (root origin) with the anatomical factors,genetic,chemical ,functional ,immunologic …etc
In simple words, there is no existential / functional relationship between the Biological factors and the symptoms of sz

To explain the main event,the hallucinations entity(s) seems as a machine that produces vocal thoughts through out waking hours without self stopping,the broadcasting of the spoken thoughts is like waves of the sea, wave after wave ,clam down or active at time,but it does not stop broadcasting the acoustic thoughts or relay (repetition) during the wakefulness period ,And
Transformation all forms of negative feeling about oneself and others,sacred personalities,religious beliefs,personal and social relationship,the society,customs and traditions,historical and contemporary events,the life and beyond, global and local phenomena,daliy life events,memories of past events related to the person’s biography

Schizophrenia does not function only during waking hours. Ever since it took control over me, I have heard voices in my dreams many times. Also, my schizophrenia controls my sleeping pattern and produces my dreams.

We have final conviction that ,most of you using the word “schizophrenia” without having determination for the nature of SZ’s nature .
Everyone of you have talking about the schizophrenia as a group of symptoms “positive,negative and cognitive…etc” -nothing else
This is fatal mistake from all aspects and leads to wrong understanding for anything related the schizophrenia

For example,
when you said “sz does not function only during waking hours”
This statement is contrary to the data of sz’s nature ,and it is so easy to prove !
simply, put the symptoms (positive,negative and cognitive ) instead of the word “schizophrenia” in the above statement ,and you will see the result !

The positive symptoms,negative and cognitive does not function only during waking hours
The question:
How the details of these symptoms occur while the person in a state of sleep / dream or unconsciousness ?

When you said" my schizophrenia controls my sleeping pattern and produces my dreams "
Put the positive symptoms,negative and cognitive instead of the word “schizophrenia” in the statement !

My positive symptoms,negative and cognitive control my sleeping pattern and produce my dreams !

The reality, the effectiveness of positive symptoms,negative and cognitive control (disordering) my will,attention and behavioral responses during the wakefulness period time and therefore it preventing both of the sleeping or dreaming !

When you said " I have heard voices in my dreams many time"
If you hear the voice you will lose the ability to follow the dream events and you will wake up to inter the world of mindfulness ,because the heard voice is spoken transmitter causing the wakefulness and attention !

I don’t notice any interruption to follow the dream events. For me the voice does not cause wakefulness or anything of that sort during sleep.

There are undoubtedly many types of schizophrenia, he said. “But clinically, 22q11DS-related schizophrenia isn’t very different from other forms of schizophrenia. Some of the mechanisms we’ve identified here may turn out to apply to those more genetically or environmentally complex types of schizophrenia.”

Sounds promising.

It’s all a bunch of crap…environment plays a role.

Like we say:
During the broadcasting period time( transmission) of the ultra audible vocal wave of the hallucination entity And its received (reception) in brain areas ,
the effect of broadcasting signal /reception will blocking the neural pathways of any transmitter who is responses to executes orders of any current functional activities (mentally,emotionally ,sensual and kinetically)

During the listening time (receiving ) the acoustic message of hallucination creature,the reception process prevents the current mental activity (without any exception at all )

In other words,during the time of transmission and reception of the Voices,
there is no any self mental signal that be transmitted from cell to other ,because the spoken transmitter of the hallucination is active in the place-time of the neural pathways ,whereas the broadcasting energy of the spoken transmitter in the brain areas is higher than the energy"s amount of the sums of mental,emotional,sensual and kinetic processes- and there no self-defense

You said" the voice does not cause wakefulness " !!!
Rally !
look,the reaction of receiving the vocal thought signal (voice) in the brain areas causing releasing an amount of neural energy which increasing the level of attention (wakefulness) over the natural rate ,and this is the basic problem that be faced by the medicine !

Increasing the level of wakefulness by broadcasting the vocal thought signal and receiving it without stop during the waking hours is the secret of schizophrenia’s effectiveness !!