Professor John McGrath from University of Queensland said NeuRA had made a “convincing case” that inflammatory processes were involved in a subgroup of people with schizophrenia.
They should help deal with negative and cognitive symptoms… oh lord…
I wonder if I got this.
“In a study published in Molecular Psychiatry, NeuRA researchers say they have identified a fourth player - the macrophage immune cell - in the brain tissue of people with “high inflammation” schizophrenia, a subgroup that accounted for 40 per cent of their overall sample.”
That’s a pretty significant subgroup. I haven’t read the study, so I don’t know how they selected their study group and if it’s likely to be similar to population averages.
Edit: it says of people with “high inflammation.” Don’t know how many people have this but it’s determined with a blood test.
Thank you for posting @anon89143308 , great news!
I can’t find the original study yet (it would probably be paywalled anyway) but I did find this:
Chronic low grade peripheral inflammation in ultra treatment resistant schizophrenia
https://www.ncbi.nlm.nih.gov/m/pubmed/29808267/
Found the original study
I gota cold so not feeling up to reading the paper, was there anything interesting in it that wasnt already pointed out?
It’s a neat discovery, but not anything that will lead to treatments in a few years. Inflammation, immune cells where they aren’t supposed to be in some people with schizophrenia - at least it’s a target, a potentially disease modifying one.
I did find this though. In this study, https://www.ncbi.nlm.nih.gov/m/pubmed/28923068/
48% of the people with schizophrenia were in the high inflammation category. Not the same study, but has some of the same authors. If 40% of those had these rogue immune cells, that would translate to roughly 20% of people with schizophrenia. Assuming, of course, they looked at the same types of inflammation, and that it ends up being replicable in larger samples.
That could be 1 in 5 though. Pretty substantial.
Edit: they also found a lower percentage (9%) of the people with schizophrenia with low inflammation also had some of these errant macrophages.
I’m trying ASHWAGANDHA to see if it will help me. My mom believes she has inflammation throughout her body and is on the Keto Diet. I consume a lot of sugar and she says that is a big culprit for inflammation.
This might explain why fish oil is great for prevention!
http://mobile.abc.net.au/news/2018-09-13/how-white-blood-cells-could-hold-key-understanding-schizophrenia/10237732?pfmredir=sm it was found in people with worse cognitive symptoms