Hi Gina,
I don’t know if anyone has studied sarcosine in sza / bipolar people - I haven’t seen any research in this area. Also - we don’t “recommend” any vitamins or supplements here - we just say that there is research that suggests that some of these might be helpful. I think you had issues with Pregnenolone - is that right? Whatever the case - I recommend you discuss it with your doctor, and also with sarcosine.
Here is the only negative reaction I’ve seen to sarcosine - a type of “irritabilty” with higher levels (2 grams+) in one person (this is part of a larger study, I believe, so nobody else had this reaction - so I guess its quite rare).
See this paper:
“we started administration of 2 g of sarcosine per day to treat persistent negative and cognitive symptoms. The patient’s activity and mood improved within 2 weeks, but in the following 2 weeks the patient reported increased drive, activity, libido, unpleasant inner tension, and irritability. We ruled out hypomania and decided to decrease the daily dose of sarcosine to 1 g, which resulted in reduction of drive and irritability. Activity and mood improved compared with his state before adding sarcosine.”
Source:
Also - was this the other supplement you tried?