i’ve always wondered this, how do meds target some areas of the brain and not others?
and how do some meds not work with some people? is it because they are actively resisting the powers of the medication or is it because of something else,
another thing i was wondering is do these meds work better if you want them to work and if so how does the med know that you want them to work in that regard i mean would they work better, sorry just got a few questions about meds and there affects,
also does the brain get use to the drug(s) you take for sz making it impossible to stop the meds even if you wanted to,
last question (a personal one) i have been taking meds for over 12 years and i was wondering if i could ever be able to come off meds? is it possible?
@asgoodasitgets I do NOt create drugs so therefore I do NOt know how they work. As for some working for some and others not so much, I have ADHD and when I take my meds I go FULL ZOMBIE. Other apparently go sky high to my levels of just being awake. I think even if you pray hard the drugs will or will NOT do what they were designed to do. It is ALL up to your body mind and soul. I think the body gets use to the drugs and that’s why people have to do or take more drugs to get the same effect as before. I think everything can be overcome if you can stay in control of your OWN mind. As for your final question that is all up to you and your doctor/s.
I honestly think that they designed the drugs for profit in mind and nothing else. Do they “help” I do NOT have the slightest clue. But I think it gives them some wiggle room to spend someone else’s hard earned dollars while we and our families have to suffer.
idk, i was kind of hoping that my mind may gradually develop to be able to stand life and all its wiles on its own without meds (one day)
i read what you said about getting some symptoms after a while and it made me think that maybe the brain needs time to adapt to any changes, like the med may have left the system but what about the brain is it messed up even more without the med as opposed to a normal healthy brain, sorry i seem to be complicating things, i think i’m a bit mixed up tbh.
Even those who did create them don’t really understand them. Vivisection on human beings is highly frowned upon.
The human body and all its organs have varied chemistry. The subsections of the brain are no different. Distribution on a biological works unevenly because of this. Only through thorough analysis of biochemical processes could one really understand how targeting works.
It’s all an automaton. And its very complex. We can only reverse engineer the processes for the most part. Until it’s fully understood then it’ll always be trial and error and shooting in the dark.
Chemistry itself is a highly probabilistic science. We can’t even simulate the systems not to the degree that the virtual interactions would ever accurately correlate with real world processes. It’s basically is quantum physics. It deals with electrons and their orbits. It also deals with molecular physics which has things spinning and vibrating with a collective momentum and the layers of complexity are difficult to get to work together. They’ll keep cracking at it though, there is obviously really really good money in coming to a certified understanding of that stuff.
@Daydreamer… I don’t know what your schizophrenia is about. If its paranoia or delusions or both. You don’t seem to mention hallucinations, but you do seem to have a lot of instability. I’d stick with your meds. Of course it is possible for you to quit taking them. Would you be better off without them, probably not.
You’re best bet is when new meds comes out That have less side effects. Latuda got less side effects but still has restlessness and vomiting. Iti-007 is only a year away from coming out if it passes testing. That’s the hope all of us have.
i can’t let this thing win, i want to beat it, i want to be normal i don’t think that thats unreasonable to think like that, everybody wants to succeed in life, to accept the inevitable seems like defeat to me and i don’t want to do that, i have always been a fighter and now even more so with a good med regime but i want to be a fighter without the need to rely on chemicals that people think controls my brain.
@Azley i read what you wrote and it seems like my questions about the meds and the brain could only be answered by some sort of pioneer in the brain/med research industry or something, its pretty sad but i guess you couldn’t have created a more unique and complicated organ than that of the brain, i think God has a lot to answer for in my opinion, i think our brain is the seat of the soul and how can you unravel someones soul esp if you can’t see it, you can’t virtually see a thought or a dream, sorry getting off topic.
Meds work by binding to receptors in the brain that would normally bind to neurotransmitters. You have different receptors in different areas of your brain, so depending on what kind of receptor the medication is targeting, it will effect different areas of your brain.
It is not really known why some meds work great for some people and others don’t. This could be because everyone’s brain chemistry is somewhat different or maybe not even everyone has the same cause behind their schizophrenia. There are many theories as to what causes schizophrenia.
Meds “working better” when you want them to work is known as the placebo effect. This is not making the medication work better, it is creating psychological effects that make you THINK it is working better. Do you know the trope in movies where someone takes a magic potion or something and they think it makes them stronger so it gives them the confidence to do something they wouldn’t normally and then they find out it wasn’t a magic potion at all? It’s the same basic process as that.
Most meds that treat schizophrenia bind to dopamine receptors and inhibit dopamine from binding, since excess dopamine is thought to cause psychotic symptoms. With the excess dopamine unable to bind and cause problems, the brain can function normally. If taken off these meds after being on them for a number of years, especially if dropping them suddenly, this causes a sudden rush of dopamine being able to bind to receptors. Your brain was used to the normal amount of dopamine that the meds were allowing and suddenly it’s overloaded. This leads to relapse and severe psychotic symptoms. Which is why…
If you want to try going off of medication WORK WITH YOUR DOCTOR. And eventual relapse is very common even if taken off gradually…remember that these meds are not a cure, they are a crutch…imagine losing your leg and getting a prosthetic. 15 years later you say “Why do I need this prosthetic! I can run fine on my own!” Then you take it off and keep falling over and can’t understand why. This is the situation that occurs when schizophrenics stop their meds.
I hope this was informative and helpful to you or anyone else with the same questions.
Just focus on the fact that its a physical world and you are physically safe. You are unimportant and so is everyone else…
No one is targeting you. There is no need for paranoia if that is what you have.
You don’t seem unorganized. Though you do seem frustrated.
Just take the pills and focus on living a good life. The more you pull your focus into that the more likely the illness will lose a hold. Reality will become clearer and life will seem more fulfilling. This may take away from your frustration and confusion.
You’re still young. Just relax… Space out… Let go of the importance… wait until an interest strikes you and do it.
A routine with some discipline like exercise… light or heavy… is a good way to learn to keep your focus and take on new challenges without the difficulties…
Most of us have times in our lives where we are extremely dissatisfied with things. Dwell on that satisfaction without finding ways to improve your life or move forward, you’re just wasting time and depressing yourself…
This is all born from my speculation… because you don’t really talk about your specific symptoms.
And buddy, you are normal. You’re more normal to us than normal people.
Learn to not talk about your illness to real life folk. “Fake it until you make it” is a valid strategy.
I mean it’s like uh… you gotta wrap your mind around the presence of your illness if you want to recognize it’s influence… and then you just have to exist outside of it and live a normal life…
I’m doing well as well… if you can look past the occasional night of relapse due to my foolish management of self…
I’m totally at peace today… the topicality has shifted and I can tell the illness no longer knows what it’s doing… and when it does bark at me in the wrong way… I just feign carelessness for its existence… brush it off and then actually become careless to it’s presence…
The voicebox loses its sense of purpose as well as its grip. The GABA seems to be working quite well… I did have a bit of sadness last night as the GABA was good enough at keeping me relaxed I didn’t need the 5HTP (serotonin.) Took one this morning after having a couple sodas just to reduce the ainx…
but uhh the one thing they kind of leave out… You’re brain does adjust its own chemistry… it’s a wonky and loose system that differs between individuals…
Basically though… the brain likes to maintain what its used to. Getting it used to higher levels of something will make it want that something (addiction)… for some reason people who feel like they should be in pain embrace their pain almost as if its supposed to be comfortable… the only way they can express their disdain for whatever scenario they’re in… they wait for someone to help them. I’m being overly general already… It’s a point to point thing…
I’m saying it because my mind is so used to having high levels of serotonin that it seems to produce more on its own. I need the 5htp less… and now I only take it to self-medicate anger/sadness… which occur less…
The GABA is general neural inhibitor. It does well to keep me relaxed and a bit more floaty… My thoughts come in slower but more clear and refined.
Overall inhibition of the neurotransmitters means that less serotonin, dopamine, norepinephrin are utilized… leaving those levels higher…
Eventually I’ll do the same thing with the GABA that I’m doing with the serotonin… Train my brain to think it needs more so it tries to produce more… then eat well enough and sleep well enough it can actually follow through with it.
buddism is good but I like my own religion, i try and not focus on anything and just give God complete control, i find it is easier this way, less responsibility.
i don’t think that thats unreasonable to think like that, everybody wants to succeed in life, to accept the inevitable seems like defeat to me and i don’t want to do that, i have always been a fighter and now even more so with a good med regime but i want to be a fighter without the need to rely on chemicals that people think controls my brain.