Psilocybin for major depression granted Breakthrough Therapy by FDA

Isn’t that the stuff in magic mushrooms? :mushroom:

What the fck is wrong with this world …

I personally never tried shrooms, but from what I heard they LITERALLY cause visual hallucinations.

Aren’t they just a milder form of LSD ?

@77nick77 ? Thoughts ?

Oh wow I did those when I was a teenager.
Walls were blue, red, green, orange — very crazy stuff.
Not recommended leaves you feeling kind of ‘incomplete’ or ‘not yourself’

I am VERY confident there is absolutely nothing medicinal about psilocybin.

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IDK @anon57786250. If they planned to treat schizophrenia with psilocybin I would think it’s a horrible idea. But treating depression with them, I wouldn’t know enough to say if it’s a good idea or not. The FDA must have some pretty strong evidence that it works. For me, yes, mushrooms seemed very similar to LSD. They last about half as long and it was a more of a mellow high which some people use as an excuse to use them. Many people used the argument that magic mushrooms are organic and natural in nature so that makes it alright to take them.

I really don’t know if the FDA is right about using psilocybin for depression. After all, back in the fifties, many thought that lobotomies were the ultimate cure for some types of mental illness. Researchers were wrong about that so I guess the FDA could be making a mistake here. Who knows?

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I was never depressed on mushrooms :stuck_out_tongue_winking_eye:

Don’t do drugs

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That’s what they said with weed too.

Do you know the mechanism of action with shrooms ?

If its treating depression then it must touch on serotonin, because the crazy visuals are caused by excessive dopamine ?

Maybe they plan to take an extract from shrooms? I would believe that more than taking it in pure form.

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Doing mushrooms is like living in a fantasy land.
The only real use I can maybe see is finding a way to extract the opiate analogs (why not just use heroin instead?) … Mushrooms is a mind blower - there is no free lunch just because it is natural and non lethal and non addictive does NOT mean it’s safe than other drugs - i tripped a few times and never ever felt like myself again

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It was just a drug to me, something to take for fun, but that’s about all I know about it. I know I couldn’t handle them now if I took some.

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I’ve done shrooms back in high school. Never had a bad trip on them lol.

I took them in high school. The only depression I had was that I was depressed because they were so hard to find anyone selling them.

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I was too scared to try shrooms lol.

:cat2:

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I put them on slices of pizza, lol. PCP was the drug that scared me.

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I tried microdosing shrooms for about six months,

It didn’t help me.

Could have been doing it wrong,

But I don’t think this is going to become a common treatment.

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Yeah, that was my buddy’s preferred method.

3 grams on a single slice of 'Za

:pizza::mushroom:

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I think psychedelic medicine could really help a sub-population of psych patients. But I think if you have psychosis these medicines probably aren’t for you

Blehhhhh. I can kick my rear all day had I known my mind would be this way after all the partying I did in HS.

im starting to wonder if they are just slowly approving every recreational drug for depression so that almost any mostly normal person can get it

I honestly see this happening.

No coffee ? No problem !

Smoke some crack ! :snowflake:

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Psilocybin has been helpful in the past for my depression, I can personally attest to psychedelics working for depression.

The problem with us though is that they won’t work for us with our antipsychotics.

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Psilocybin has already had promising results for people with MDD:

[“The results from previous studies clearly demonstrate the remarkable potential for psilocybin as a treatment in MDD patients, which Usona is now seeking to confirm in its own clinical trials,” says Usona’s director of clinical and translational research, Charles Raison. “What is truly groundbreaking is FDA’s rightful acknowledgement that MDD, not just the much smaller treatment-resistant depression population, represents an unmet medical need and that the available data suggest that psilocybin may offer a substantial clinical improvement over existing therapies.”]

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