Promising steps made towards hope for schizophrenia treatment

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The negative symptoms in schizophrenia cause significant distress to patients but there are no approved treatments. That is because the nature of the changes in brain chemistry that contribute to these negative symptoms is unknown.

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This PET scan research shows that alteration in brain chemicals in striatum contributes to development of negative symptoms

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This analysis revealed a marked global increase in connection of MOR availability in patients with schizophrenia, this was more pronounced in the connection of brain circuit called cerebello-thalamo-cortical network

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Mu opioid #receptor availability decreased in brains of people with# schizophrenia who died as result of #suicide