“Schizophrenia symptoms are believed to be caused by miscommunication between brain areas. The miscommunication may be caused by lack of synchronization of the activity of neurons in the brain. Normalizing synchronization of neurons is expected to improve communication between brain areas and thereby threat the symptoms of schizophrenia. This is yet to be confirmed in clinical studies, but data is very robust as we have tested the approach in different DNA-mutations leading to schizophrenia and the identified treatments were able to normalize brain cell function in all of them.”
Lundbeck is also the company partnering with Vanderbilt University on their new muscarinic drug.