In therapeutic doses, amisupride antagonises postsynaptic dopamine D2 and D3 receptors, but in low doses, it enhances dopaminergic neurotransmission by preferentially blocking presynaptic dopamine D2/D3 autoreceptors - does this mean that in low doses, amisulpride could cause psychosis?
My psychiatrist said that she wants to try me on Amisulpride, because they think I’m at risk for schizophrenia. I was going to ask them about the possibility of starting off low and slowly building up over the coming weeks/months, but if I start low, it sounds like things could get worse?
I see you’ve been reading the text on Wikipedia on Amisulpride - I don’t think anyone here has the necessary degree in neuropsychopharmacology to be able to answer question with any certainty - but one of the questions is what does “low” mean in this situation. I recommend you discuss this issue with your psychiatrist and your pharmacist.
Yeah thanks @SzAdmin. I’ll talk to my doctor next week. It’s just that I’ve been prescribed medication for subjective disorganized thoughts and was getting a little anxious but I’m sure my doctor will be able to clear things up
